Fig. 3. NF-κB activation and Akt phosphorylation were increased after postconditioning in mice. (A) The effects of postconditioning on the NF-κB pathway were confirmed using western blot analysis. Postconditioning increased nuclear translocation of p65, especially at 1 and 4 h reperfusion following tMCAO. Postconditioning increased the phosphorylation of Akt after tMCAO in mice. (B) Relative changes in the amount of pAkt and p65 protein after tMCAO and postconditioning; difference from the sham group (#p<0.05, ##p<0.01) and from the tMCAO group (*p<0.05, ***p<0.001). Data are mean±SE. n=5.
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