Fig. 3. The mRNA expression of immune-related molecules and cytokines 1 week after spinal cord injury. CD11b, macrophage marker, expressed similar between EC and Agm (A). Arg-1 and CD206, M2 macrophage marker, were significantly increased in Agm (B&C). Inflammatory cytokines, IL-1b and IL-6 were not changed with agmatine treatment (Agm) or without (EC, D&E) but IL-10, anti-inflammatory cytokine, was significantly increased in Agm (F). Agmatine treatment group (Agm, n=5); Experimental control group (EC, n=5). *p<0.05.
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