Fig. 3. Mice which experienced MS or MSEW did not exhibit impairments in hippocampal and amygdala-dependent fear-related emotional memories. In the acquisition phase of the fear conditioning test, there were no significant difference between (A) MS and MC mice and (B) MSEW and MC mice in the percent freezing time when exposed to the conditioned stimulus (tone) paired with the unconditioned stimulus (foot shock). Habit, Habituation; US, Unconditioned Stimulus; CS, Conditioned Stimulus. Three mice from the MC group in the MSEW cohort were excluded for severe injuries. During the contextual fear recall 24 hours after training, there were no significant differences between (C) MS and MC mice and (D) MSEW and MC mice on percent freezing time. During the cue fear recall 24 hours after training, there was also no significant differences between (E) MS and MC mice and (F) MSEW and MC mice on percent freezing time. One mice from MS and MSEW group were each excluded as outliers for low freezing responses. All values are means±SEM.
© Exp Neurobiol
