Fig. 2. Theta power modulation by ICSS. (A) Average trace of the wheel-turning activity of six mice. Dotted vertical lines indicate the onset (time=0) and the cessation (time=10) of the MFB stimulation. Gray shades for SEM. (B) Mean duration of the wheel-turning activity. *for p<0.05, repeated measures ANOVA and post hoc comparison with the Tukey-Kramer method. Error bars for SEM. (C, E) Average spectrograms of the PFC EEG and HPC LFP data. (D, F) Average power spectral density during the pre-ICSS, the ICSS and the post-ICSS sessions in the PFC and the HPC, respectively. Gray shades indicate the frequency range of the theta rhythm (6~10 Hz), where a significant difference was found in the PFC between the pre-ICSS and ICSS sessions. *for p<0.05, Wilcoxon signed rank test. Error bars for SEM. (G) Representative traces of the raw signals and corresponding theta-filtered signals for the PFC EEG and the HPC LFP data. Scale of the EEG and LFP data were matched by normalization.
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