Fig. 5. Neuronal and oligodendrocyte proteins were down-regulated in CTE. (A) Heat map analysis showed that neuronal markers such as CAMKV, CAMK2A, CALM, CFL1 and 2, MAP2, and TUBB3 are down regulated in the cortex of post mortem brains of CTE patients. Red color represents the higher expression while green color represents the lower expression of protein. (B) Heat map analysis showed that oligodendrocyte (OGD) markers such as CNP, ERMN, ENPP6, MBP isoforms (3, 4, and 6), MAG, and TUBB4 are down-regulated in the cortex of post mortem brains of CTE patients. Color scale was based on the log2 transformed expression values of proteins in CTE patients or normal subjects.
© Exp Neurobiol
