Download original image
Fig. 1. Degeneration of DA neurons in the substantia nigra in LRRK2 R1441G mutant mice. DA neurons were detected by TH-specific antibody. LRRK2 R1441G mutation decreased TH positive DA neurons at 10~11 months (Normal: R1441G=8:8), 15~16 months (Normal: R1441G=7:7), and 20~24 months (Normal: R1441G=7:7) of age (*<0.05). Data are expressed as the mean±SEM. Scale bars indicate 50 μm.
Exp Neurobiol. 2019;28:504~515 https://doi.org/10.5607/en.2019.28.4.504
© Exp Neurobiol