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Fig. 3. Quality assessment of LPS-induced mouse model at 10 days post-LPS peritoneal injection. (A) Timeline of the experimental design. Eight-week-old mice were injected with LPS or PBS; then behavior tests were done at day 10 post injection. The animals were sacrificed immediately after behavior test for volumetric analysis. (B) Volumetric data does not correlate with body weight, brain weight or habenula size. (C) Duration of immobility was measured during the last 4 min of the 6-min test session. Dots represent values of individual mice and vertical lines indicate SEM (PBS, n=8, LPS, n=7 mice; **p<0.01).
Experimental Neurobiology 2019;28:709~719
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