Frequencies of B cell subsets in 4 groups (naïve: IgD+CD27−, double-negative: IgD−CD27−, unswitched memory: IgD+CD27+, switched memory: IgD−CD27+)
| Group | 1 | 2 | 3 | 4 | p-value |
|---|---|---|---|---|---|
| Naïve | 73.99±12.61 | 56.63±21.08 | 69.44±16.14 | 69.00±8.07 | 0.2466 |
| UM | 5.40±2.19 | 5.48±2.90 | 5.19±2.57 | 6.20±1.5 | 0.8475 |
| SM | 15.78±8.47 | 24.65±11.68 | 20.26±13.42 | 16.97±3.73 | 0.4078 |
| DN | 4.83±3.36 | 13.23±9.40 | 5.11±1.98 | 7.81±4.06 | 0.0828 |
Although none of 4 subsets revealed statistically significant difference between 4 groups, group 2 showed marked increase of double-negative B cells and relative decrease of naïve B cells. Data were presented as mean±standard deviation. UM, unswitched memory B cells; SM, switched memory B cells; DN, double-negative B cells.