Transcripts differentially expressed in group 4, 2 versus 1 and their fold changes

Disease activity (group 4 vs 1)ISTX effect (group 2 vs 1)


Up-regulatedDown-regulatedUp-regulatedDown-regulated
CCR2 (4.71)CD83 (5.55)IL10RA (2.74)CD45RB (3.88)DUSP4 (2.96)
CD45RB (4.4)DUSP4 (5.54)ICAM1 (2.67)EGR1 (3.1)LGALS3 (2.44)
LAIR (2.53)NFKBIA (4.97)ICOSLG (2.52)IFIT2 (2.44)NOD2 (2.2)
SLAMF6 (2.4)SOCS3 (4.68)NFKBIZ (2.42)LILRB2 (2.3)GBP5 (2.11)
BCL6 (2.34)CXCR4 (4.51)PRDM1 (2.36)LAIR1 (2.25)PRDM1 (2.05)
TGFBI (2.34)BCL3 (4.37)CCND3 (2.33)EBI3 (2.19)
IL7 (2.33)CD96 (3.66)CDKN1A (2.23)EGR2 (2.16)
TLR4 (2.2)BCL2L11 (3.19)CCL5 (2.21)BCL6 (2.16)
HRE (2)FKBP5 (2.89)HLA-DRB1 (2.17)NFIL3 (2.08)
TNFAIP3 (2.89)TRAF4 (2.16)HRE (2.08)
IRF1 (2.83)GBP5 (2.11)
CCR7 (2.76)IL13RA1 (2.07)
SOCS1 (2.74)NOD2 (2.05)

Among the 4 lists of differentially regulated genes, only those down-regulated in group 4 compared to group 1 revealed significant functional annotation clusters, shown in Table 4.

Experimental Neurobiology 2019;28:720~726 https://doi.org/10.5607/en.2019.28.6.720
© Exp Neurobiol