Dendritic spine dynamics of different mPFC regions’ pyramidal neurons during different memory processes

Region Layer Memory stage Spine density Spine morphology Reference
ACC II/III Consolidation Increased ? [15]
V/VI Consolidation Baseline ? [81]
II/III Consolidation Increased Enlarged [81, 93]
II/III Extinction Baseline Sustained [93]
PL - Consolidation Increased ? [52]
V Extinction Decreased ? [94]
IL II/III Consolidation Increased Increased [93]
II/III Extinction Sustained Baseline [93]
Exp Neurobiol 2022;31:221~231 https://doi.org/10.5607/en22012
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