en Experimental Neurobiology

Cited by CrossRef (141)

  1. Amanda Sierra, Sol Beccari, Irune Diaz-Aparicio, Juan M. Encinas, Samuel Comeau, Marie-Ève Tremblay. Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis. Neural Plasticity 2014;2014:1
    https://doi.org/10.1155/2014/610343
  2. Alanna G. Spiteri, Claire L. Wishart, Nicholas J. C. King. Immovable Object Meets Unstoppable Force? Dialogue Between Resident and Peripheral Myeloid Cells in the Inflamed Brain. Front. Immunol. 2020;11
    https://doi.org/10.3389/fimmu.2020.600822
  3. Jiah Pearson-Leary, Chunyu Zhao, Kyle Bittinger, Darrell Eacret, Sandra Luz, Abigail S. Vigderman, Gabriel Dayanim, Seema Bhatnagar. The gut microbiome regulates the increases in depressive-type behaviors and in inflammatory processes in the ventral hippocampus of stress vulnerable rats. Mol Psychiatry 2020;25:1068
    https://doi.org/10.1038/s41380-019-0380-x
  4. Carlo Pancaro, Julie Boulanger-Bertolus, Scott Segal, Chris J. Watson, Irene St Charles, George A. Mashour, James E. Marchand. Maternal Noninfectious Fever Enhances Cell Proliferation and Microglial Activation in the Neonatal Rat Dentate Gyrus. 2019;128:1190
    https://doi.org/10.1213/ANE.0000000000004051
  5. Zhi-Gang Wang, Lei Wang, Don C. Lamb, Hua-Jie Chen, Yusi Hu, Hong-Peng Wang, Dai-Wen Pang, Shu-Lin Liu. Real-Time Dissecting the Dynamics of Drug Transportation in the Live Brain. Nano Lett. 2021;21:642
    https://doi.org/10.1021/acs.nanolett.0c04216
  6. Luisa Möhle, Pablo Bascuñana, Mirjam Brackhan, Jens Pahnke. Development of deep learning models for microglia analyses in brain tissue using DeePathology™ STUDIO. Journal of Neuroscience Methods 2021;364:109371
    https://doi.org/10.1016/j.jneumeth.2021.109371
  7. Ali Ertürk, Susanne Mentz, Erik E. Stout, Maj Hedehus, Sara L. Dominguez, Lisa Neumaier, Franziska Krammer, Gemma Llovera, Karpagam Srinivasan, David V. Hansen, Arthur Liesz, Kimberly A. Scearce-Levie, Morgan Sheng. Interfering with the Chronic Immune Response Rescues Chronic Degeneration After Traumatic Brain Injury. J. Neurosci. 2016;36:9962
    https://doi.org/10.1523/JNEUROSCI.1898-15.2016
  8. Andrew Campbell, Jared Bushman, Joshua Munger, Mark Noble, Christoph Pröschel, Margot Mayer‐Pröschel. Mutation of ataxia–telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia. Glia 2016;64:227
    https://doi.org/10.1002/glia.22925
  9. Xin Wang, Kai Zhang, Fanmuyi Yang, Zhenhua Ren, Mei Xu, Jacqueline A. Frank, Zun-ji Ke, Jia Luo. Minocycline protects developing brain against ethanol-induced damage. Neuropharmacology 2018;129:84
    https://doi.org/10.1016/j.neuropharm.2017.11.019
  10. Jeney Ramírez-Sánchez, Elisa Nicoloso Simões Pires, Yanier Nuñez-Figueredo, Gilberto L. Pardo-Andreu, Luis Arturo Fonseca-Fonseca, Alberto Ruiz-Reyes, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, René Delgado-Hernández, Diogo O. Souza, Christianne Salbego. Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway. Neurochemistry International 2015;90:215
    https://doi.org/10.1016/j.neuint.2015.09.003
  11. Jonathan W. VanRyzin, Sheryl E. Arambula, Sydney E. Ashton, Alexa C. Blanchard, Max D. Burzinski, Katherine T. Davis, Serena Edwards, Emily L. Graham, Amanda Holley, Katherine E. Kight, Ashley E. Marquardt, Miguel Perez-Pouchoulen, Lindsay A. Pickett, Erin L. Reinl, Margaret M. McCarthy. Generation of an Iba1-EGFP Transgenic Rat for the Study of Microglia in an Outbred Rodent Strain. eNeuro 2021;8:ENEURO.0026-21.2021
    https://doi.org/10.1523/ENEURO.0026-21.2021
  12. Andrea G. Edlow, Ruthy M Glass, Caroline J Smith, Phuong Kim Tran, Kaitlyn James, Staci Bilbo. Placental Macrophages: A Window Into Fetal Microglial Function in Maternal Obesity. Intl J of Devlp Neuroscience 2019;77:60
    https://doi.org/10.1016/j.ijdevneu.2018.11.004
  13. Navina L Chrobok, John G J M Bol, Micha M M Wilhelmus, Benjamin Drukarch, Anne-Marie van Dam. Tissue Transglutaminase Appears in Monocytes and Macrophages but Not in Lymphocytes in White Matter Multiple Sclerosis Lesions. 2019;78:492
    https://doi.org/10.1093/jnen/nlz030
  14. Petr Zach, Jana Mrzílková, Jan Pala, Libor Uttl, Viera Kútna, Vladimír Musil, Blanka Sommerová, Petr Tůma. New Design of the Electrophoretic Part of CLARITY Technology for Confocal Light Microscopy of Rat and Human Brains. Brain Sciences 2019;9:218
    https://doi.org/10.3390/brainsci9090218
  15. Athanasios Lourbopoulos, Ali Ertürk, Farida Hellal. Microglia in action: how aging and injury can change the brain’s guardians. Front. Cell. Neurosci. 2015;9
    https://doi.org/10.3389/fncel.2015.00054
  16. Christina Nürnberg, Norbert Kociok, Claudia Brockmann, Timo Lischke, Sergio Crespo-Garcia, Nadine Reichhart, Susanne Wolf, Ria Baumgrass, Sabine A. Eming, Sandra Beer-Hammer, Antonia M. Joussen. Myeloid cells contribute indirectly to VEGF expression upon hypoxia via activation of Müller cells. Experimental Eye Research 2018;166:56
    https://doi.org/10.1016/j.exer.2017.10.011
  17. Jessica M. Noll, Catherine J. Augello, Esra Kürüm, Liuliu Pan, Anna Pavenko, Andy Nam, Byron D. Ford. Spatial Analysis of Neural Cell Proteomic Profiles Following Ischemic Stroke in Mice Using High-Plex Digital Spatial Profiling. Mol Neurobiol 2022;59:7236
    https://doi.org/10.1007/s12035-022-03031-x
  18. Yung-Hui Kuan, Hsi-Chien Shih, Sung-Chun Tang, Jiann-Shing Jeng, Bai-Chuang Shyu. Targeting P2X7 receptor for the treatment of central post-stroke pain in a rodent model. Neurobiology of Disease 2015;78:134
    https://doi.org/10.1016/j.nbd.2015.02.028
  19. Joseph Ochaba, Alex Mas Monteys, Jacqueline G. O’Rourke, Jack C. Reidling, Joan S. Steffan, Beverly L. Davidson, Leslie M. Thompson. PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo. Neuron 2016;90:507
    https://doi.org/10.1016/j.neuron.2016.03.016
  20. Darwin Yang, Sarah J. Yang, Jackson Travis Del Bonis-O’Donnell, Rebecca L. Pinals, Markita P. Landry. Mitigation of Carbon Nanotube Neurosensor Induced Transcriptomic and Morphological Changes in Mouse Microglia with Surface Passivation. ACS Nano 2020;14:13794
    https://doi.org/10.1021/acsnano.0c06154
  21. Xiao-Ling Fang, Shao-Yun Ding, Xiao-Zheng Du, Jin-Hai Wang, Xing-Lan Li. Ferroptosis—A Novel Mechanism With Multifaceted Actions on Stroke. Front. Neurol. 2022;13
    https://doi.org/10.3389/fneur.2022.881809
  22. Changyoun Kim, He-Jin Lee, Eliezer Masliah, Seung-Jae Lee. Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2. Exp Neurobiol 2016;25:113
    https://doi.org/10.5607/en.2016.25.3.113
  23. Gregory Artiushin, Amita Sehgal. The Glial Perspective on Sleep and Circadian Rhythms. Annu. Rev. Neurosci. 2020;43:119
    https://doi.org/10.1146/annurev-neuro-091819-094557
  24. Christina B. Schroeter, Alexander M. Herrmann, Stefanie Bock, Anna Vogelsang, Susann Eichler, Philipp Albrecht, Sven G. Meuth, Tobias Ruck. One Brain—All Cells: A Comprehensive Protocol to Isolate All Principal CNS-Resident Cell Types from Brain and Spinal Cord of Adult Healthy and EAE Mice. Cells 2021;10:651
    https://doi.org/10.3390/cells10030651
  25. Chesarahmia Dojo Soeandy, Faraz Salmasi, Maya Latif, Andrew J. Elia, Nan Ji Suo, Jeffrey T. Henderson. Endothelin-1-mediated cerebral ischemia in mice: early cellular events and the role of caspase-3. Apoptosis 2019;24:578
    https://doi.org/10.1007/s10495-019-01541-z
  26. Dong-Joo Choi, Jiawei An, Ilo Jou, Sang Myun Park, Eun-Hye Joe. A Parkinson's disease gene, DJ-1, regulates anti-inflammatory roles of astrocytes through prostaglandin D2 synthase expression. Neurobiology of Disease 2019;127:482
    https://doi.org/10.1016/j.nbd.2019.04.003
  27. Farnaz Nikbakht, Rafie Belali, Homa Rasoolijazi, Ali Mohammad khanizadeh. 2-Deoxyglucose protects hippocampal neurons against kainate-induced temporal lobe epilepsy by modulating monocyte-derived macrophages (mo-MΦ) and progranulin production in the hippocampus. Neuropeptides 2019;76:101932
    https://doi.org/10.1016/j.npep.2019.05.003
  28. Zhenhua Ren, Xin Wang, Mei Xu, Jacqueline A. Frank, Jia Luo. Minocycline attenuates ethanol-induced cell death and microglial activation in the developing spinal cord. Alcohol 2019;79:25
    https://doi.org/10.1016/j.alcohol.2018.12.002
  29. Nicole I. Wolf, Marjolein Breur, Bonnie Plug, Shanice Beerepoot, Aimee S. R. Westerveld, Diane F. van Rappard, Sharon I. de Vries, Maarten H. P. Kole, Adeline Vanderver, Marjo S. van der Knaap, Caroline A. Lindemans, Peter M. van Hasselt, Jaap J. Boelens, Ulrich Matzner, Volkmar Gieselmann, Marianna Bugiani. Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction. Ann Clin Transl Neurol 2020;7:169
    https://doi.org/10.1002/acn3.50975
  30. Claudia Espinosa‐García, Claudia Erika Fuentes‐Venado, Christian Guerra‐Araiza, Julia Segura‐Uribe, Edwin Chávez‐Gutiérrez, Eunice Dalet Farfán‐García, Norma Angélica Estrada Cruz, Rodolfo Pinto‐Almazán. Sex differences in the performance of cognitive tasks in a murine model of metabolic syndrome. Eur J of Neuroscience 2020;52:2724
    https://doi.org/10.1111/ejn.14751
  31. Elysha Nur Ismail, Ibrahim Jantan, Sharmili Vidyadaran, Jamia Azdina Jamal, Norazrina Azmi. Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways. BMC Complement Med Ther 2020;20
    https://doi.org/10.1186/s12906-020-02961-0
  32. Inken Waltl, Christopher Käufer, Sonja Bröer, Chintan Chhatbar, Luca Ghita, Ingo Gerhauser, Muneeb Anjum, Ulrich Kalinke, Wolfgang Löscher. Macrophage depletion by liposome-encapsulated clodronate suppresses seizures but not hippocampal damage after acute viral encephalitis. Neurobiology of Disease 2018;110:192
    https://doi.org/10.1016/j.nbd.2017.12.001
  33. Edward J. R. Fletcher, Clare J. Finlay, Ana Amor Lopez, William R. Crum, Anthony C. Vernon, Susan Duty. Neuroanatomical and Microglial Alterations in the Striatum of Levodopa-Treated, Dyskinetic Hemi-Parkinsonian Rats. Front. Neurosci. 2020;14
    https://doi.org/10.3389/fnins.2020.567222
  34. Tsogzolmaa Ganbold, Qingming Bao, Jargalmaa Zandan, Agula Hasi, Huricha Baigude. Modulation of Microglia Polarization through Silencing of NF-κB p65 by Functionalized Curdlan Nanoparticle-Mediated RNAi. ACS Appl. Mater. Interfaces 2020;12:11363
    https://doi.org/10.1021/acsami.9b23004
  35. Ahmed Sharaf, Brian Roos, Raissa Timmerman, Gert-Jan Kremers, Jeffrey John Bajramovic, Angelo Accardo. Two-Photon Polymerization of 2.5D and 3D Microstructures Fostering a Ramified Resting Phenotype in Primary Microglia. Front. Bioeng. Biotechnol. 2022;10
    https://doi.org/10.3389/fbioe.2022.926642
  36. Lara Bergdolt, Anna Dunaevsky. Brain changes in a maternal immune activation model of neurodevelopmental brain disorders. Progress in Neurobiology 2019;175:1
    https://doi.org/10.1016/j.pneurobio.2018.12.002
  37. Prashant Hariharan, Carolyn A. Harris. Cerebrospinal Fluid Disorders. 2019.
    https://doi.org/10.1007/978-3-319-97928-1_17
  38. Qing You, Xiao-bing Lan, Ning Liu, Juan Du, Lin Ma, Jia-mei Yang, Jian-guo Niu, Xiao-dong Peng, Gui-lin Jin, Jian-qiang Yu. Neuroprotective strategies for neonatal hypoxic-ischemic brain damage: Current status and challenges. European Journal of Pharmacology 2023;957:176003
    https://doi.org/10.1016/j.ejphar.2023.176003
  39. Mirjana Nacka-Aleksić, Marija Stojanović, Lidija Simić, Biljana Bufan, Jelena Kotur-Stevuljević, Zorica Stojić-Vukanić, Mirjana Dimitrijević, Slavica Ražić, Gordana Leposavić. Sex as a determinant of age-related changes in rat spinal cord inflammation-oxidation state. Biogerontology 2017;18:821
    https://doi.org/10.1007/s10522-017-9726-4
  40. Benjamin B. Tournier, Stergios Tsartsalis, Kelly Ceyzériat, Valentina Garibotto, Philippe Millet. In Vivo TSPO Signal and Neuroinflammation in Alzheimer’s Disease. Cells 2020;9:1941
    https://doi.org/10.3390/cells9091941
  41. Chao Huang, Jili Wang, Xu Lu, Wenfeng Hu, Feng Wu, Bo Jiang, Yong Ling, Rongrong Yang, Wei Zhang. Z-guggulsterone negatively controls microglia-mediated neuroinflammation via blocking IκB-α–NF-κB signals. Neuroscience Letters 2016;619:34
    https://doi.org/10.1016/j.neulet.2016.02.021
  42. Agnieszka Ścibior, Konrad A. Szychowski, Iwona Zwolak, Klaudia Dachowska, Jan Gmiński. In vitro effect of vanadyl sulfate on cultured primary astrocytes: cell viability and oxidative stress markers.. J of Applied Toxicology 2020;40:737
    https://doi.org/10.1002/jat.3939
  43. Amy C. Reichelt, Amy Loughman, Ashton Bernard, Mukesh Raipuria, Kirsten N Abbott, James Dachtler, Thi Thu Hao Van, Robert J. Moore. An intermittent hypercaloric diet alters gut microbiota, prefrontal cortical gene expression and social behaviours in rats. Nutritional Neuroscience 2020;23:613
    https://doi.org/10.1080/1028415X.2018.1537169
  44. Nay Chi Nway, Yuji Fujitani, Seishiro Hirano, Ohn Mar, Tin-Tin Win-Shwe. Role of TLR4 in olfactory-based spatial learning activity of neonatal mice after developmental exposure to diesel exhaust origin secondary organic aerosol. NeuroToxicology 2017;63:155
    https://doi.org/10.1016/j.neuro.2017.10.001
  45. Nicola Mattugini, Juliane Merl‐Pham, Elisabetta Petrozziello, Lisa Schindler, Jürgen Bernhagen, Stefanie M. Hauck, Magdalena Götz. Influence of white matter injury on gray matter reactive gliosis upon stab wound in the adult murine cerebral cortex. Glia 2018;66:1644
    https://doi.org/10.1002/glia.23329
  46. Bianca Hutter-Schmid, Christian Humpel. Primary mouse brain pericytes isolated from transgenic Alzheimer mice spontaneously differentiate into a CD11b+ microglial-like cell type in vitro. Experimental Gerontology 2018;112:30
    https://doi.org/10.1016/j.exger.2018.08.003
  47. Young Ock Kim, Hak Jae Kim, Gasem Mohammad Abu-Taweel, Junsang Oh, Gi-Ho Sung. Neuroprotective and therapeutic effect of Cordyceps militaris on ischemia-induced neuronal death and cognitive impairments. Saudi Journal of Biological Sciences 2019;26:1352
    https://doi.org/10.1016/j.sjbs.2018.08.011
  48. Jyoti Gautam, Jeffrey H. Miner, Yao Yao. Loss of Endothelial Laminin α5 Exacerbates Hemorrhagic Brain Injury. Transl. Stroke Res. 2019;10:705
    https://doi.org/10.1007/s12975-019-0688-5
  49. K.A. Jones, S. Maltby, M.W. Plank, M. Kluge, M. Nilsson, P.S. Foster, F.R. Walker. Peripheral immune cells infiltrate into sites of secondary neurodegeneration after ischemic stroke. Brain, Behavior, and Immunity 2018;67:299
    https://doi.org/10.1016/j.bbi.2017.09.006
  50. J Pearson-Leary, D Eacret, R Chen, H Takano, B Nicholas, S Bhatnagar. Inflammation and vascular remodeling in the ventral hippocampus contributes to vulnerability to stress. Transl Psychiatry 2017;7:e1160
    https://doi.org/10.1038/tp.2017.122
  51. Konrad Rejdak, Halina Sienkiewicz‐Jarosz, Przemyslaw Bienkowski, Anton Alvarez. Modulation of neurotrophic factors in the treatment of dementia, stroke and TBI: Effects of Cerebrolysin. Medicinal Research Reviews 2023;43:1668
    https://doi.org/10.1002/med.21960
  52. Inés Corraliza. Recruiting specialized macrophages across the borders to restore brain functions. Front. Cell. Neurosci. 2014;8
    https://doi.org/10.3389/fncel.2014.00262
  53. Nattayaporn Apaijai, Dalila Monica Moisescu, Siripong Palee, Christian Mervyn McSweeney, Napatsorn Saiyasit, Chayodom Maneechote, Chiraphat Boonnag, Nipon Chattipakorn, Siriporn C. Chattipakorn. Pretreatment With PCSK9 Inhibitor Protects the Brain Against Cardiac Ischemia/Reperfusion Injury Through a Reduction of Neuronal Inflammation and Amyloid Beta Aggregation. JAHA 2019;8
    https://doi.org/10.1161/JAHA.118.010838
  54. Wonju Kim, Minji Kim, Beomsue Kim. Unraveling the enigma: housekeeping gene Ugt1a7c as a universal biomarker for microglia. Front. Psychiatry 2024;15
    https://doi.org/10.3389/fpsyt.2024.1364201
  55. Hey-Kyeong Jeong, Ilo Jou, Eun-Hye Joe. Absence of Delayed Neuronal Death in ATP-Injected Brain: Possible Roles of Astrogliosis. Exp Neurobiol 2013;22:308
    https://doi.org/10.5607/en.2013.22.4.308
  56. Lynn van Olst, Sigrid J.M. Roks, Alwin Kamermans, Barbara J. H. Verhaar, Anne M. van der Geest, Majon Muller, Wiesje M. van der Flier, Helga E. de Vries. Contribution of Gut Microbiota to Immunological Changes in Alzheimer’s Disease. Front. Immunol. 2021;12
    https://doi.org/10.3389/fimmu.2021.683068
  57. Chao Huang, Xu Lu, Jia Wang, Lijuan Tong, Bo Jiang, Wei Zhang. Inhibition of endogenous heat shock protein 70 attenuates inducible nitric oxide synthase induction via disruption of heat shock protein 70/Na+/H+ exchanger 1‐Ca2+‐calcium‐calmodulin‐dependent protein kinase II/transforming growth factor β‐activated kinase 1‐nuclear factor‐κB signals in BV‐2 microglia. J of Neuroscience Research 2015;93:1192
    https://doi.org/10.1002/jnr.23571
  58. Insup Choi, Beomsue Kim, Ji-Won Byun, Sung Hoon Baik, Yun Hyun Huh, Jong-Hyeon Kim, Inhee Mook-Jung, Woo Keun Song, Joo-Ho Shin, Hyemyung Seo, Young Ho Suh, Ilo Jou, Sang Myun Park, Ho Chul Kang, Eun-Hye Joe. LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase. Nat Commun 2015;6
    https://doi.org/10.1038/ncomms9255
  59. Andrea Becerra-Calixto, Rafael Posada-Duque, Gloria Patricia Cardona-Gómez. Recovery of Neurovascular Unit Integrity by CDK5-KD Astrocyte Transplantation in a Global Cerebral Ischemia Model. Mol Neurobiol 2018;55:8563
    https://doi.org/10.1007/s12035-018-0992-1
  60. Yi Li, Ning Chen, Chao Wu, Yongquan Lu, Ge Gao, Chunli Duan, Hui Yang, Lingling Lu. Galectin-1 attenuates neurodegeneration in Parkinson’s disease model by modulating microglial MAPK/IκB/NFκB axis through its carbohydrate-recognition domain. Brain, Behavior, and Immunity 2020;83:214
    https://doi.org/10.1016/j.bbi.2019.10.015
  61. Yahaira Naaldijk, Lauren S. Sherman, Natalia Turrini, Yannick Kenfack, Mariusz Z. Ratajczak, Nizar Souayah, Pranela Rameshwar, Henning Ulrich. Mesenchymal Stem Cell—Macrophage Crosstalk Provides Specific Exosomal Cargo to Direct Immune Response Licensing of Macrophages during Inflammatory Responses. Stem Cell Rev and Rep 2024;20:218
    https://doi.org/10.1007/s12015-023-10612-3
  62. Nataša Mrvová, Martin Škandík, Štefan Bezek, Lucia Račková. Protective Effect of Semisynthetic and Natural Flavonoid on Aged Rat Microglia–enriched Cultures. Neurotox Res 2019;36:844
    https://doi.org/10.1007/s12640-019-00071-5
  63. Wolfgang Löscher, Charles L. Howe. Molecular Mechanisms in the Genesis of Seizures and Epilepsy Associated With Viral Infection. Front. Mol. Neurosci. 2022;15
    https://doi.org/10.3389/fnmol.2022.870868
  64. Rasmus Rydbirk, Betina Elfving, Mille Dahl Andersen, Mia Aggergaard Langbøl, Jonas Folke, Kristian Winge, Bente Pakkenberg, Tomasz Brudek, Susana Aznar. Cytokine profiling in the prefrontal cortex of Parkinson's Disease and Multiple System Atrophy patients. Neurobiology of Disease 2017;106:269
    https://doi.org/10.1016/j.nbd.2017.07.014
  65. Tamotsu Tsukahara, Yasuka Sahara, Nigel Ribeiro, Ryoko Tsukahara, Mari Gotoh, Satoshi Sakamoto, Hiroshi Handa, Kimiko Murakami-Murofushi. Adenine nucleotide translocase 2, a putative target protein for 2-carba cyclic phosphatidic acid in microglial cells. Cellular Signalling 2021;82:109951
    https://doi.org/10.1016/j.cellsig.2021.109951
  66. Dario Valdinocci, Gary D. Grant, Tracey C. Dickson, Dean L. Pountney. Epothilone D inhibits microglia-mediated spread of alpha-synuclein aggregates. Molecular and Cellular Neuroscience 2018;89:80
    https://doi.org/10.1016/j.mcn.2018.04.006
  67. Kristen A. Milleville, Nabil Awan, Dominic Disanto, Raj G. Kumar, Amy K. Wagner. Early chronic systemic inflammation and associations with cognitive performance after moderate to severe TBI. Brain, Behavior, & Immunity - Health 2021;11:100185
    https://doi.org/10.1016/j.bbih.2020.100185
  68. Navrinder Kaur, Heerak Chugh, Meena K. Sakharkar, Uma Dhawan, Saravana Babu Chidambaram, Ramesh Chandra. Neuroinflammation Mechanisms and Phytotherapeutic Intervention: A Systematic Review. ACS Chem. Neurosci. 2020;11:3707
    https://doi.org/10.1021/acschemneuro.0c00427
  69. Sung Eun Lee, Haijie Yang, Youngjun Sung, Younghoon Kim, Sun Ah Park. Region-Specific Differences in the Apoe4-dependent Response to Focal Brain Injury. Exp Neurobiol 2021;30:285
    https://doi.org/10.5607/en21022
  70. Hyun Joo Shin, Eun Ae Jeong, Jong Youl Lee, Hyeong Seok An, Hye Min Jang, Yu Jeong Ahn, Jaewoong Lee, Kyung Eun Kim, Gu Seob Roh. Lipocalin-2 Deficiency Reduces Oxidative Stress and Neuroinflammation and Results in Attenuation of Kainic Acid-Induced Hippocampal Cell Death. Antioxidants 2021;10:100
    https://doi.org/10.3390/antiox10010100
  71. Roberta Ströher Toledo, Dirson João Stein, Paulo Roberto Stefani Sanches, Lisiane Santos da Silva, Helouise Richardt Medeiros, Felipe Fregni, Wolnei Caumo, Iraci L.S. Torres. rTMS induces analgesia and modulates neuroinflammation and neuroplasticity in neuropathic pain model rats. Brain Research 2021;1762:147427
    https://doi.org/10.1016/j.brainres.2021.147427
  72. Chesarahmia Dojo Soeandy, Andrew J. Elia, Yanshan Cao, Christopher Rodgers, Shudi Huang, Andrea C. Elia, Jeffrey T. Henderson. Necroptotic–Apoptotic Regulation in an Endothelin-1 Model of Cerebral Ischemia. Cell Mol Neurobiol 2021;41:1727
    https://doi.org/10.1007/s10571-020-00942-y
  73. Tae Nyoung Chung, Jin Hee Kim, Bo Young Choi, Ju-Yeon Jeong, Sung Phil Chung, Sung Won Kwon, Sang Won Suh. Effect of Adipose-Derived Mesenchymal Stem Cell Administration and Mild Hypothermia Induction on Delayed Neuronal Death After Transient Global Cerebral Ischemia. 2017;45:e508
    https://doi.org/10.1097/CCM.0000000000002289
  74. Eun-Hye Joe, Dong-Joo Choi, Jiawei An, Jin-Hwa Eun, Ilo Jou, Sangmyun Park. Astrocytes, Microglia, and Parkinson’s Disease. Exp Neurobiol 2018;27:77
    https://doi.org/10.5607/en.2018.27.2.77
  75. Noriko Taguchi, Shin Nakayama, Makoto Tanaka. Single administration of soluble epoxide hydrolase inhibitor suppresses neuroinflammation and improves neuronal damage after cardiac arrest in mice. Neuroscience Research 2016;111:56
    https://doi.org/10.1016/j.neures.2016.05.002
  76. Elaine Dempsey, Áine Abautret-Daly, Neil G. Docherty, Carlos Medina, Andrew Harkin. Persistent central inflammation and region specific cellular activation accompany depression- and anxiety-like behaviours during the resolution phase of experimental colitis. Brain, Behavior, and Immunity 2019;80:616
    https://doi.org/10.1016/j.bbi.2019.05.007
  77. Pete A. Williams, Catherine E. Braine, Krishnakumar Kizhatil, Nicole E. Foxworth, Nicholas G. Tolman, Jeffrey M. Harder, Rebecca A. Scott, Gregory L. Sousa, Alyssa Panitch, Gareth R. Howell, Simon W. M. John. Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma. Mol Neurodegeneration 2019;14
    https://doi.org/10.1186/s13024-018-0303-3
  78. Tayebeh Noori, Ahmad Reza Dehpour, Antoni Sureda, Sajad Fakhri, Eduardo Sobarzo-Sanchez, Mohammad Hosein Farzaei, Esra Küpeli Akkol, Zahra Khodarahmi, Seyede Zahra Hosseini, Seyede Darya Alavi, Samira Shirooie. The role of glycogen synthase kinase 3 beta in multiple sclerosis. Biomedicine & Pharmacotherapy 2020;132:110874
    https://doi.org/10.1016/j.biopha.2020.110874
  79. Alex Portes, Elizabeth Giestal-de-Araujo, Aline Fagundes, Pablo Pandolfo, Arnaldo de Sá Geraldo, Marie Luce Flores Lira, Veronica Figueiredo Amaral, Jussara Lagrota-Candido. Leishmania amazonensis infection induces behavioral alterations and modulates cytokine and neurotrophin production in the murine cerebral cortex. Journal of Neuroimmunology 2016;301:65
    https://doi.org/10.1016/j.jneuroim.2016.11.003
  80. Amery Treble-Barna, Valentina Pilipenko, Shari L. Wade, Anil G. Jegga, Keith Owen Yeates, H. Gerry Taylor, Lisa J. Martin, Brad G. Kurowski. Cumulative Influence of Inflammatory Response Genetic Variation on Long-Term Neurobehavioral Outcomes after Pediatric Traumatic Brain Injury Relative to Orthopedic Injury: An Exploratory Polygenic Risk Score. Journal of Neurotrauma 2020;37:1491
    https://doi.org/10.1089/neu.2019.6866
  81. Han-Gyu Bae, Tai Kyoung Kim, Ho Young Suk, Sangyoung Jung, Dong-Gyu Jo. White matter and neurological disorders. Arch. Pharm. Res. 2020;43:920
    https://doi.org/10.1007/s12272-020-01270-x
  82. Jong-hyeon Kim, Ilo Jou, Eun-Hye Joe. Suppression of miR-155 Expression in IFN-γ-Treated Astrocytes and Microglia by DJ-1: A Possible Mechanism for Maintaining SOCS1 Expression. Exp Neurobiol 2014;23:148
    https://doi.org/10.5607/en.2014.23.2.148
  83. Carmen Infante-Garcia, Monica Garcia-Alloza. Review of the Effect of Natural Compounds and Extracts on Neurodegeneration in Animal Models of Diabetes Mellitus. IJMS 2019;20:2533
    https://doi.org/10.3390/ijms20102533
  84. Jean Lud Cadet, Veronica Bisagno. Glial-neuronal ensembles: partners in drug addiction-associated synaptic plasticity. Front. Pharmacol. 2014;5
    https://doi.org/10.3389/fphar.2014.00204
  85. Fabiana Galland, Juliana Santos de Espindola, Daniel Saraiva Lopes, Milena Ferreira Taccola, Maria Teresa Bertoldo Pacheco. Food-derived bioactive peptides: Mechanisms of action underlying inflammation and oxidative stress in the central nervous system. Food Chemistry Advances 2022;1:100087
    https://doi.org/10.1016/j.focha.2022.100087
  86. Anne Sebastiani, Frederik Greve, Christina Gölz, Carola Y. Förster, Hermann Koepsell, Serge C. Thal. RS1 (Rsc1A1) deficiency limits cerebral SGLT1 expression and delays brain damage after experimental traumatic brain injury. Journal of Neurochemistry 2018;147:190
    https://doi.org/10.1111/jnc.14551
  87. A.K. Wagner, R.G. Kumar. TBI Rehabilomics Research: Conceptualizing a humoral triad for designing effective rehabilitation interventions. Neuropharmacology 2019;145:133
    https://doi.org/10.1016/j.neuropharm.2018.09.011
  88. Nisha Patro, Ishan Patro. The Biology of Glial Cells: Recent Advances. 2019.
    https://doi.org/10.1007/978-981-16-8313-8_7
  89. Beimeng Yang, David M. Figueroa, Yujun Hou, Mansi Babbar, Stephanie L. Baringer, Deborah L. Croteau, Vilhelm A. Bohr. NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress. Free Radical Biology and Medicine 2019;141:47
    https://doi.org/10.1016/j.freeradbiomed.2019.05.037
  90. Seyed Esmaeil Khoshnam, William Winlow, Maryam Farzaneh, Yaghoob Farbood, Hadi Fathi Moghaddam. Pathogenic mechanisms following ischemic stroke. Neurol Sci 2017;38:1167
    https://doi.org/10.1007/s10072-017-2938-1
  91. Joseph Ochaba, Gianna Fote, Marketta Kachemov, Soe Thein, Sylvia Y. Yeung, Alice L. Lau, Sarah Hernandez, Ryan G. Lim, Malcolm Casale, Michael J. Neel, Edwin S. Monuki, Jack Reidling, David E. Housman, Leslie M. Thompson, Joan S. Steffan. IKKβ slows Huntington’s disease progression in R6/1 mice. Proc. Natl. Acad. Sci. U.S.A. 2019;116:10952
    https://doi.org/10.1073/pnas.1814246116
  92. Edwards III, Gamez, Armijo, Kramm, Morales, Taylor-Presse, Schulz, Soto, Moreno-Gonzalez. Peripheral Delivery of Neural Precursor Cells Ameliorates Parkinson’s Disease-Associated Pathology. Cells 2019;8:1359
    https://doi.org/10.3390/cells8111359
  93. Keun-Ryung Bae, Hyun-Jung Shim, Deebika Balu, Sang Ryong Kim, Seong-Woon Yu. Translocator Protein 18 kDa Negatively Regulates Inflammation in Microglia. J Neuroimmune Pharmacol 2014;9:424
    https://doi.org/10.1007/s11481-014-9540-6
  94. Zixiu Zeng, Yunling Zhang, Xiao Liang, Fengli Wang, Jiayi Zhao, Zhenmin Xu, Xiaohan Liu, Xuemei Liu. Qingnao dripping pills mediate immune-inflammatory response and MAPK signaling pathway after acute ischemic stroke in rats. Journal of Pharmacological Sciences 2019;139:143
    https://doi.org/10.1016/j.jphs.2018.12.009
  95. Rachel Gilfarb, Zoe Tapp, Elise Lemanski, John Velasquez, Sydney Cornelius, Olga N. Kokiko-Cochran, Benedetta Leuner. Multiparity Differentially Affects Specific Aspects of the Acute Neuroinflammatory Response to Traumatic Brain Injury in Female Mice. Neuroscience 2023;511:86
    https://doi.org/10.1016/j.neuroscience.2022.12.011
  96. Zhengzhao Liu, Hongming Li, Chungu Hong, Menglu Chen, Tao Yue, Chunyuan Chen, Zhenxing Wang, Qing You, Chuanyin Li, Qinjie Weng, Hui Xie, Ronggui Hu. ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death. Front. Immunol. 2018;9
    https://doi.org/10.3389/fimmu.2018.02647
  97. Sushupta M. Vijapur, Leah E. Vaughan, Nabil Awan, Dominic DiSanto, Gina P. McKernan, Amy K. Wagner. Treelet transform analysis to identify clusters of systemic inflammatory variance in a population with moderate-to-severe traumatic brain injury. Brain, Behavior, and Immunity 2021;95:45
    https://doi.org/10.1016/j.bbi.2021.01.026
  98. Marie-Gabrielle Goossens, Lars Emil Larsen, Marijke Vergaelen, Wytse Wadman, Chris Van den Haute, Wayra Brackx, Silke Proesmans, Jana Desloovere, Emma Christiaen, Erine Craey, Christian Vanhove, Kristl Vonck, Paul Boon, Robrecht Raedt. Level of hM4D(Gi) DREADD Expression Determines Inhibitory and Neurotoxic Effects in the Hippocampus. eNeuro 2021;8:ENEURO.0105-21.2021
    https://doi.org/10.1523/ENEURO.0105-21.2021
  99. Raj G. Kumar, Jonathan E. Rubin, Rachel P. Berger, Patrick M. Kochanek, Amy K. Wagner. Principal components derived from CSF inflammatory profiles predict outcome in survivors after severe traumatic brain injury. Brain, Behavior, and Immunity 2016;53:183
    https://doi.org/10.1016/j.bbi.2015.12.008
  100. Kitty Reemst, Stephen C. Noctor, Paul J. Lucassen, Elly M. Hol. The Indispensable Roles of Microglia and Astrocytes during Brain Development. Front. Hum. Neurosci. 2016;10
    https://doi.org/10.3389/fnhum.2016.00566
  101. Bokyung Song, Sung-Joong Lee, Chong-Hyun Kim. Roles of Cytokines in the Temporal Changes of Microglial Membrane Currents and Neuronal Excitability and Synaptic Efficacy in ATP-Induced Cortical Injury Model. IJMS 2021;22:6853
    https://doi.org/10.3390/ijms22136853
  102. Saurabh Dhanda, Smriti Gupta, Avishek Halder, Aditya Sunkaria, Rajat Sandhir. Systemic inflammation without gliosis mediates cognitive deficits through impaired BDNF expression in bile duct ligation model of hepatic encephalopathy. Brain, Behavior, and Immunity 2018;70:214
    https://doi.org/10.1016/j.bbi.2018.03.002
  103. Qian Li, Xi Lan, Xiaoning Han, Jian Wang. Expression of Tmem119/Sall1 and Ccr2/CD69 in FACS-Sorted Microglia- and Monocyte/Macrophage-Enriched Cell Populations After Intracerebral Hemorrhage. Front. Cell. Neurosci. 2019;12
    https://doi.org/10.3389/fncel.2018.00520
  104. Shubhanchi Nigam, Lauren McCarl, Rajeev Kumar, Robert S. Edinger, Brenda F. Kurland, Carolyn J. Anderson, Ashok Panigrahy, Gary Kohanbash, W. Barry Edwards. Preclinical ImmunoPET Imaging of Glioblastoma-Infiltrating Myeloid Cells Using Zirconium-89 Labeled Anti-CD11b Antibody. Mol Imaging Biol 2020;22:685
    https://doi.org/10.1007/s11307-019-01427-1
  105. Kyla R. Rodgers, Yufan Lin, Thomas J. Langan, Yoichiro Iwakura, Richard C. Chou. Innate Immune Functions of Astrocytes are Dependent Upon Tumor Necrosis Factor-Alpha. Sci Rep 2020;10
    https://doi.org/10.1038/s41598-020-63766-2
  106. Christopher E. G. Uff, Karishma Patel, Charming Yeung, Ping K. Yip. Advances in Visualizing Microglial Cells in Human Central Nervous System Tissue. Biomolecules 2022;12:603
    https://doi.org/10.3390/biom12050603
  107. Sheu-Ran Choi, Alvin J Beitz, Jang-Hern Lee. Spinal Nitric Oxide Synthase Type II Increases Neurosteroid-metabolizing Cytochrome P450c17 Expression in a Rodent Model of Neuropathic Pain. Exp Neurobiol 2019;28:516
    https://doi.org/10.5607/en.2019.28.4.516
  108. Trong Thanh Han, Tung Nguyen Duy, Lam Nguyen Dang Son, Hinh Nguyen Van, Tuan Do Trong, Dung Nguyen Viet, Dung Nguyen Tuan, Luu Vu Dang. Features extraction of MRI image using complex network with low computational complexity to distinguish inflammatory lesions from tumors in the human brain. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization 2023;11:94
    https://doi.org/10.1080/21681163.2022.2055493
  109. Po-Yi Chen, Celeste Yin-Chieh Wu, Garrett A. Clemons, Cristiane T. Citadin, Alexandre Couto e Silva, Harlee E. Possoit, Rinata Azizbayeva, Nathan E. Forren, Chin-Hung Liu, K.N. Shashanka Rao, David M. Krzywanski, Reggie Hui-Chao Lee, Jake T. Neumann, Hung Wen Lin. Stearic acid methyl ester affords neuroprotection and improves functional outcomes after cardiac arrest. Prostaglandins, Leukotrienes and Essential Fatty Acids 2020;159:102138
    https://doi.org/10.1016/j.plefa.2020.102138
  110. Dandan Zhou, Lei Ji, Youguo Chen. TSPO Modulates IL-4-Induced Microglia/Macrophage M2 Polarization via PPAR-γ Pathway. J Mol Neurosci 2020;70:542
    https://doi.org/10.1007/s12031-019-01454-1
  111. Bohao Zhang, Yunwei Ran, Siting Wu, Fang Zhang, Huachen Huang, Changlian Zhu, Shusheng Zhang, Xiaoan Zhang. Inhibition of Colony Stimulating Factor 1 Receptor Suppresses Neuroinflammation and Neonatal Hypoxic-Ischemic Brain Injury. Front. Neurol. 2021;12
    https://doi.org/10.3389/fneur.2021.607370
  112. Masatake Toshimitsu, Yoshimasa Kamei, Mari Ichinose, Takahiro Seyama, Shinya Imada, Takayuki Iriyama, Tomoyuki Fujii. Atomoxetine, a selective norepinephrine reuptake inhibitor, improves short‐term histological outcomes after hypoxic‐ischemic brain injury in the neonatal male rat. Intl J of Devlp Neuroscience 2018;70:34
    https://doi.org/10.1016/j.ijdevneu.2018.03.011
  113. R. König, P. Rotheneichner, J. Marschallinger, L. Aigner, S. Couillard-Despres. Adult Neurogenesis in the Hippocampus. 2018.
    https://doi.org/10.1016/B978-0-12-801977-1.00007-6
  114. Jong-hyeon Kim, Dong-joo Choi, Hey-kyeong Jeong, Jun Kim, Dae Won Kim, Soo Young Choi, Sang-Myun Park, Young Ho Suh, Ilo Jou, Eun-Hye Joe. DJ-1 facilitates the interaction between STAT1 and its phosphatase, SHP-1, in brain microglia and astrocytes: A novel anti-inflammatory function of DJ-1. Neurobiology of Disease 2013;60:1
    https://doi.org/10.1016/j.nbd.2013.08.007
  115. Luise Klein, Daan R.M.G. Ophelders, Daniel van den Hove, Maurits Damoiseaux, Bart P.F. Rutten, Chris P.M. Reutelingsperger, Leon J. Schurgers, Tim G.A.M. Wolfs. Prenatal administration of multipotent adult progenitor cells modulates the systemic and cerebral immune response in an ovine model of chorioamnionitis. Brain, Behavior, & Immunity - Health 2022;23:100458
    https://doi.org/10.1016/j.bbih.2022.100458
  116. Fang-Yi Long, Meng-Qi Shi, Hong-Jing Zhou, Dong-Ling Liu, Na Sang, Jun-Rong Du. Klotho upregulation contributes to the neuroprotection of ligustilide against cerebral ischemic injury in mice. European Journal of Pharmacology 2018;820:198
    https://doi.org/10.1016/j.ejphar.2017.12.019
  117. Sabrina Salberg, Jennaya Christensen, Glenn R. Yamakawa, Connor Lengkeek, Haris Malik, Jason Tabor, Ali Hazari, Richelle Mychasiuk. A Bump on the Head or Late to Bed: Behavioral and Pathophysiological Effects of Sleep Deprivation after Repetitive Mild Traumatic Brain Injury in Adolescent Rats. Journal of Neurotrauma 2018;35:1895
    https://doi.org/10.1089/neu.2018.5744
  118. Romina María Uranga, Jeffrey Neil Keller. The Complex Interactions Between Obesity, Metabolism and the Brain. Front. Neurosci. 2019;13
    https://doi.org/10.3389/fnins.2019.00513
  119. Agnieszka M. Jurga, Martyna Paleczna, Katarzyna Z. Kuter. Overview of General and Discriminating Markers of Differential Microglia Phenotypes. Front. Cell. Neurosci. 2020;14
    https://doi.org/10.3389/fncel.2020.00198
  120. Allison Costello, Katrina Linning-Duffy, Carleigh Vandenbrook, Joseph S. Lonstein, Lily Yan. Daytime Light Deficiency Leads to Sex- and Brain Region-Specific Neuroinflammatory Responses in a Diurnal Rodent. Cell Mol Neurobiol 2023;43:1369
    https://doi.org/10.1007/s10571-022-01256-x
  121. Magnus Sabel, Marie Kalm, Thomas Björk-Eriksson, Birgitta Lannering, Klas Blomgren. Hypothermia after cranial irradiation protects neural progenitor cells in the subventricular zone but not in the hippocampus. International Journal of Radiation Biology 2017;93:771
    https://doi.org/10.1080/09553002.2017.1321810
  122. Pete A. Williams, Catherine E. Braine, Nicole E. Foxworth, Kelly E. Cochran, Simon W. M. John. GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma. J Neuroinflammation 2017;14
    https://doi.org/10.1186/s12974-017-0868-8
  123. Panagiotis Perdikaris, Catherine R. Dermon. Altered GABAergic, glutamatergic and endocannabinoid signaling is accompanied by neuroinflammatory response in a zebrafish model of social withdrawal behavior. Front. Mol. Neurosci. 2023;16
    https://doi.org/10.3389/fnmol.2023.1120993
  124. Nutchareeporn Nillert, Wanassanun Pannangrong, Jariya Welbat, Wunnee Chaijaroonkhanarak, Kittisak Sripanidkulchai, Bungorn Sripanidkulchai. Neuroprotective Effects of Aged Garlic Extract on Cognitive Dysfunction and Neuroinflammation Induced by β-Amyloid in Rats. Nutrients 2017;9:24
    https://doi.org/10.3390/nu9010024
  125. Rengasamy Balakrishnan, Duk-Yeon Cho, In-Su Kim, Sang-Ho Seol, Dong-Kug Choi. Molecular Mechanisms and Therapeutic Potential of α- and β-Asarone in the Treatment of Neurological Disorders. Antioxidants 2022;11:281
    https://doi.org/10.3390/antiox11020281
  126. Sarah R. Anderson, Jianmin Zhang, Michael R. Steele, Cesar O. Romero, Amanda G. Kautzman, Dorothy P. Schafer, Monica L. Vetter. Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J. Neurosci. 2019;39:2025
    https://doi.org/10.1523/JNEUROSCI.1854-18.2018
  127. Dale B. Bosco, Dai‐Shi Tian, Long‐Jun Wu. Neuroimmune interaction in seizures and epilepsy: focusing on monocyte infiltration. The FEBS Journal 2020;287:4822
    https://doi.org/10.1111/febs.15428
  128. Lidia Castro, Montoya Noelia, Marian Vidal-Jorge, David Sánchez-Ortiz, Darío Gándara, Elena Martínez-Saez, Marta Cicuéndez, Maria-Antonia Poca, J. Marc Simard, Juan Sahuquillo. Kir6.2, the Pore-Forming Subunit of ATP-Sensitive K+ Channels, Is Overexpressed in Human Posttraumatic Brain Contusions. Journal of Neurotrauma 2019;36:165
    https://doi.org/10.1089/neu.2017.5619
  129. Laura Zelenka, Dennis Pägelow, Christina Krüger, Jana Seele, Friederike Ebner, Sebastian Rausch, Manfred Rohde, Seija Lehnardt, Kira van Vorst, Marcus Fulde. Novel protocol for the isolation of highly purified neonatal murine microglia and astrocytes. Journal of Neuroscience Methods 2022;366:109420
    https://doi.org/10.1016/j.jneumeth.2021.109420
  130. Hey-Kyeong Jeong, Kyung-Min Ji, Kyoung-Jin Min, Insup Choi, Dong-Joo Choi, Ilo Jou, Eun-Hye Joe. Astrogliosis Is a Possible Player in Preventing Delayed Neuronal Death. Molecules and Cells 2014;37:345
    https://doi.org/10.14348/molcells.2014.0046
  131. Sanjay Kumar, Brennetta J. Crenshaw, Sparkle D. Williams, Courtnee’ R. Bell, Qiana L. Matthews, Brian Sims. Cocaine‐Specific Effects on Exosome Biogenesis in Microglial Cells. Neurochem Res 2021;46:1006
    https://doi.org/10.1007/s11064-021-03231-2
  132. Leonardo P. Mesquita, Rafael C. Costa, Laís L. R. Mesquita, Maria do Carmo C. S. H. Lara, Eliana M. C. Villalobos, Claudia M. C. Mori, Enio Mori, Elizabeth W. Howerth, Paulo C. Maiorka. Pathogenesis of Equid Alphaherpesvirus 1 Infection in the Central Nervous System of Mice. Vet Pathol 2021;58:1075
    https://doi.org/10.1177/03009858211020670
  133. Masaaki Iwata, Hisahito Ishida, Koichi Kaneko, Yukihiko Shirayama. Learned helplessness activates hippocampal microglia in rats: A potential target for the antidepressant imipramine. Pharmacology Biochemistry and Behavior 2016;150-151:138
    https://doi.org/10.1016/j.pbb.2016.10.005
  134. Suraj Kumar, Rishabha Malviya. Protein and peptide from blue food for neurological disorder: Advances and prospective. Trends in Food Science & Technology 2024;143:104277
    https://doi.org/10.1016/j.tifs.2023.104277
  135. Gaku Yamanaka, Shinichiro Morichi, Tomoko Takamatsu, Yusuke Watanabe, Shinji Suzuki, Yu Ishida, Shingo Oana, Takashi Yamazaki, Fuyuko Takata, Hisashi Kawashima. Links between Immune Cells from the Periphery and the Brain in the Pathogenesis of Epilepsy: A Narrative Review. IJMS 2021;22:4395
    https://doi.org/10.3390/ijms22094395
  136. Luciano Stürmer de Fraga, Isadora D’Ávila Tassinari, Jeferson Jantsch, Renata Padilha Guedes, Victorio Bambini-Junior. ‘A picture is worth a thousand words’: The use of microscopy for imaging neuroinflammation. 2021;206:325
    https://doi.org/10.1111/cei.13669
  137. Raj G. Kumar, Jennifer A. Boles, Amy K. Wagner. Chronic Inflammation After Severe Traumatic Brain Injury. 2015;30:369
    https://doi.org/10.1097/HTR.0000000000000067
  138. Yupeng Dong, Yoshitaka Kimura, Takuya Ito, Clarissa Velayo, Takafumi Sato, Rika Sugibayashi, Kiyoe Funamoto, Kudo Hitomi, Keita Iida, Miyuki Endo, Naoaki Sato, Nobuo Yaegashi. Vaginal LPS changed gene transcriptional regulation response to ischemic reperfusion and increased vulnerability of fetal brain hemorrhage. Biochemical and Biophysical Research Communications 2015;468:228
    https://doi.org/10.1016/j.bbrc.2015.10.125
  139. Lucio D’Anna, Graham Searle, Kirsten Harvey, Paul M. Matthews, Roland Veltkamp. Time course of neuroinflammation after human stroke – a pilot study using co-registered PET and MRI. BMC Neurol 2023;23
    https://doi.org/10.1186/s12883-023-03178-7
  140. Richard L. Jayaraj, Sheikh Azimullah, Rami Beiram, Fakhreya Y. Jalal, Gary A. Rosenberg. Neuroinflammation: friend and foe for ischemic stroke. J Neuroinflammation 2019;16
    https://doi.org/10.1186/s12974-019-1516-2
  141. Thura Tun Oo, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C. Chattipakorn. Emerging roles of toll-like receptor 4 in chemotherapy-induced neurotoxicity. NeuroToxicology 2022;93:112
    https://doi.org/10.1016/j.neuro.2022.09.006