en Experimental Neurobiology

Cited by CrossRef (27)

  1. Wenbin Wan, Lan Cao, Bill Kalionis, Shijin Xia, Xiantao Tai. Applications of Induced Pluripotent Stem Cells in Studying the Neurodegenerative Diseases. Stem Cells International 2015;2015:1
    https://doi.org/10.1155/2015/382530
  2. Charles R. Goodlett, Megan Stringer, Jonathan LaCombe, Roshni Patel, Joseph M. Wallace, Randall J. Roper. Evaluation of the therapeutic potential of Epigallocatechin-3-gallate (EGCG) via oral gavage in young adult Down syndrome mice. Sci Rep 2020;10
    https://doi.org/10.1038/s41598-020-67133-z
  3. Esteban J. Rozen, Julia Roewenstrunk, María José Barallobre, Chiara Di Vona, Carole Jung, Ana F. Figueiredo, Jeroni Luna, Cristina Fillat, Maria L. Arbonés, Mariona Graupera, Miguel A. Valverde, Susana de la Luna. DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells. Cell Reports 2018;23:1867
    https://doi.org/10.1016/j.celrep.2018.04.008
  4. Laura E. Meissner, Ellen F. Macnamara, Precilla D'Souza, John Yang, Gilbert Vezina, Carlos R. Ferreira, Wadih M. Zein, Cynthia J. Tifft, David R. Adams, Maria T. Acosta, Margaret Adam, David R. Adams, Pankaj B. Agrawal, Mercedes E. Alejandro, Justin Alvey, Laura Amendola, Ashley Andrews, Euan A. Ashley, Mahshid S. Azamian, Carlos A. Bacino, Guney Bademci, Eva Baker, Ashok Balasubramanyam, Dustin Baldridge, Jim Bale, Michael Bamshad, Deborah Barbouth, Pinar Bayrak‐Toydemir, Anita Beck, Alan H. Beggs, Edward Behrens, Gill Bejerano, Jimmy Bennet, Beverly Berg‐Rood, Jonathan A. Bernstein, Gerard T. Berry, Anna Bican, Stephanie Bivona, Elizabeth Blue, John Bohnsack, Carsten Bonnenmann, Devon Bonner, Lorenzo Botto, Brenna Boyd, Lauren C. Briere, Elly Brokamp, Gabrielle Brown, Elizabeth A. Burke, Lindsay C. Burrage, Manish J. Butte, Peter Byers, William E. Byrd, John Carey, Olveen Carrasquillo, Ta Chen Peter Chang, Sirisak Chanprasert, Hsiao‐Tuan Chao, Gary D. Clark, Terra R. Coakley, Laurel A. Cobban, Joy D. Cogan, Matthew Coggins, F. Sessions Cole, Heather A. Colley, Cynthia M. Cooper, Heidi Cope, William J. Craigen, Andrew B. Crouse, Michael Cunningham, Precilla D'Souza, Hongzheng Dai, Surendra Dasari, Mariska Davids, Jyoti G. Dayal, Matthew Deardorff, Esteban C. Dell'Angelica, Shweta U. Dhar, Katrina Dipple, Daniel Doherty, Naghmeh Dorrani, Emilie D. Douine, David D. Draper, Laura Duncan, Dawn Earl, David J. Eckstein, Lisa T. Emrick, Christine M. Eng, Cecilia Esteves, Tyra Estwick, Marni Falk, Liliana Fernandez, Carlos Ferreira, Elizabeth L. Fieg, Laurie C. Findley, Paul G. Fisher, Brent L. Fogel, Irman Forghani, Laure Fresard, William A. Gahl, Ian Glass, Rena A. Godfrey, Katie Golden‐Grant, Alica M. Goldman, David B. Goldstein, Alana Grajewski, Catherine A. Groden, Andrea L. Gropman, Irma Gutierrez, Sihoun Hahn, Rizwan Hamid, Neil A. Hanchard, Kelly Hassey, Nichole Hayes, Frances High, Anne Hing, Fuki M. Hisama, Ingrid A. Holm, Jason Hom, Martha Horike‐Pyne, Alden Huang, Yong Huang, Rosario Isasi, Fariha Jamal, Gail P. Jarvik, Jeffrey Jarvik, Suman Jayadev, Jean M. Johnston, Lefkothea Karaviti, Emily G. Kelley, Jennifer Kennedy, Dana Kiley, Isaac S. Kohane, Jennefer N. Kohler, Deborah Krakow, Donna M. Krasnewich, Elijah Kravets, Susan Korrick, Mary Koziura, Joel B. Krier, Seema R. Lalani, Byron Lam, Christina Lam, Brendan C. Lanpher, Ian R. Lanza, C Christopher Lau, Kimberly LeBlanc, Brendan H. Lee, Hane Lee, Roy Levitt, Richard A. Lewis, Sharyn A. Lincoln, Pengfei Liu, Xue Zhong Liu, Nicola Longo, Sandra K. Loo, Joseph Loscalzo, Richard L. Maas, Ellen F. Macnamara, Calum A. MacRae, Valerie V. Maduro, Marta M. Majcherska, Bryan Mak, May Christine V. Malicdan, Laura A. Mamounas, Teri A. Manolio, Rong Mao, Kenneth Maravilla, Thomas C. Markello, Ronit Marom, Gabor Marth, Beth A. Martin, Martin G. Martin, Julian A. Martínez‐Agosto, Shruti Marwaha, Jacob McCauley, Allyn McConkie‐Rosell, Colleen E. McCormack, Alexa T. McCray, Elisabeth McGee, Heather Mefford, J. Lawrence Merritt, Matthew Might, Ghayda Mirzaa, Eva Morava, Paolo M. Moretti, Marie Morimoto, John J. Mulvihill, David R. Murdock, Mariko Nakano‐Okuno, Avi Nath, Stan F. Nelson, John H. Newman, Sarah K. Nicholas, Deborah Nickerson, Shirley Nieves‐Rodriguez, Donna Novacic, Devin Oglesbee, James P. Orengo, Laura Pace, Stephen Pak, J. Carl Pallais, Christina G. S. Palmer, Jeanette C. Papp, Neil H. Parker, John A. Phillips, Jennifer E. Posey, Lorraine Potocki, Barbara N. Pusey, Aaron Quinlan, Wendy Raskind, Archana N. Raja, Deepak A. Rao, Genecee Renteria, Chloe M. Reuter, Lynette Rives, Amy K. Robertson, Lance H. Rodan, Jill A. Rosenfeld, Natalie Rosenwasser, Maura Ruzhnikov, Ralph Sacco, Jacinda B. Sampson, Susan L. Samson, Mario Saporta, C. Ron Scott, Judy Schaechter, Timothy Schedl, Kelly Schoch, Daryl A. Scott, Prashant Sharma, Vandana Shashi, Jimann Shin, Rebecca Signer, Catherine H. Sillari, Edwin K. Silverman, Janet S. Sinsheimer, Kathy Sisco, Edward C. Smith, Kevin S. Smith, Emily Solem, Lilianna Solnica‐Krezel, Rebecca C. Spillmann, Joan M. Stoler, Nicholas Stong, Jennifer A. Sullivan, Kathleen Sullivan, Angela Sun, Shirley Sutton, David A. Sweetser, Virginia Sybert, Holly K. Tabor, Cecelia P. Tamburro, Queenie K.‐G. Tan, Mustafa Tekin, Fred Telischi, Willa Thorson, Cynthia J. Tifft, Camilo Toro, Alyssa A. Tran, Brianna M. Tucker, Tiina K. Urv, Adeline Vanderver, Matt Velinder, Dave Viskochil, Tiphanie P. Vogel, Colleen E. Wahl, Stephanie Wallace, Nicole M. Walley, Chris A. Walsh, Melissa Walker, Jennifer Wambach, Jijun Wan, Lee‐kai Wang, Michael F. Wangler, Patricia A. Ward, Daniel Wegner, Mark Wener, Tara Wenger, Katherine Wesseling Perry, Monte Westerfield, Matthew T. Wheeler, Jordan Whitlock, Lynne A. Wolfe, Jeremy D. Woods, Shinya Yamamoto, John Yang, Guoyun Yu, Diane B. Zastrow, Chunli Zhao, Stephan Zuchner. DYRK1A pathogenic variants in two patients with syndromic intellectual disability and a review of the literature . Mol. Genet. Genomic Med. 2020;8
    https://doi.org/10.1002/mgg3.1544
  5. Cristina Grau, Krisztina Arató, José M. Fernández-Fernández, Aitana Valderrama, Carlos Sindreu, Cristina Fillat, Isidre Ferrer, Susana de la Luna, Xavier Altafaj. DYRK1A-mediated phosphorylation of GluN2A at Ser1048 regulates the surface expression and channel activity of GluN1/GluN2A receptors. Front. Cell. Neurosci. 2014;8
    https://doi.org/10.3389/fncel.2014.00331
  6. Mina Yousefelahiyeh, Jingyi Xu, Estibaliz Alvarado, Yang Yu, David Salven, Robert M. Nissen, Arun Rishi. DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B. PLoS ONE 2018;13:e0207779
    https://doi.org/10.1371/journal.pone.0207779
  7. Nobuhiro Kurabayashi, Minh Dang Nguyen, Kamon Sanada. DYRK 1A overexpression enhances STAT activity and astrogliogenesis in a Down syndrome mouse model . EMBO Rep 2015;16:1548
    https://doi.org/10.15252/embr.201540374
  8. Arnaud Duchon, Yann Herault. DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome. Front. Behav. Neurosci. 2016;10
    https://doi.org/10.3389/fnbeh.2016.00104
  9. Megan Stringer, Charles R. Goodlett, Randall J. Roper. Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits. Mol Genet Genomic Med 2017;5:451
    https://doi.org/10.1002/mgg3.334
  10. Joshua D. Blazek, Irushi Abeysekera, Jiliang Li, Randall J. Roper. Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomicDyrk1a. Hum. Mol. Genet. 2015;24:5687
    https://doi.org/10.1093/hmg/ddv284
  11. Farrah Rajabi, Jonathan D. Picker. New Innovations: Therapies for Genetic Conditions. Curr Genet Med Rep 2014;2:113
    https://doi.org/10.1007/s40142-014-0043-9
  12. Esti Wahyu Widowati, Sabrina Ernst, Ralf Hausmann, Gerhard Müller-Newen, Walter Becker. Functional characterization of DYRK1A missense variants associated with a syndromic form of intellectual deficiency and autism. Biology Open 2018;7:bio032862
    https://doi.org/10.1242/bio.032862
  13. Julie L. Lefebvre, Julie Marocha. Cellular Migration and Formation of Axons and Dendrites. 2018.
    https://doi.org/10.1016/B978-0-12-814407-7.00012-2
  14. Masashi Asai, Takashi Kawakubo, Ryotaro Mori, Nobuhisa Iwata. Elucidating Pathogenic Mechanisms of Early-onset Alzheimer's Disease in Down Syndrome Patients. YAKUGAKU ZASSHI 2017;137:801
    https://doi.org/10.1248/yakushi.16-00236-2
  15. Eunju Im, Kwang Chul Chung. Dyrk1A phosphorylates parkin at Ser-131 and negatively regulates its ubiquitin E3 ligase activity. J. Neurochem. 2015;134:756
    https://doi.org/10.1111/jnc.13164
  16. Susana García-Cerro, Noemí Rueda, Verónica Vidal, Sara Lantigua, Carmen Martínez-Cué. Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes. Neurobiology of Disease 2017;106:76
    https://doi.org/10.1016/j.nbd.2017.06.010
  17. Sara Anna Bonini, Andrea Mastinu, Giulia Ferrari-Toninelli, Maurizio Memo. Potential Role of Microtubule Stabilizing Agents in Neurodevelopmental Disorders. IJMS 2017;18:1627
    https://doi.org/10.3390/ijms18081627
  18. Qiang Wang, Zhuangzhuang Geng, Yi Gong, Kaitlyn Warren, Haiyan Zheng, Yuka Imamura, Zhonghua Gao. WDR68 is essential for the transcriptional activation of the PRC1-AUTS2 complex and neuronal differentiation of mouse embryonic stem cells. Stem Cell Research 2018;33:206
    https://doi.org/10.1016/j.scr.2018.10.023
  19. Maria del Mar Muñiz Moreno, Véronique Brault, Marie-Christine Birling, Guillaume Pavlovic, Yann Herault. Preclinical Research in Down Syndrome: Insights for Pathophysiology and Treatments. 2018.
    https://doi.org/10.1016/bs.pbr.2019.08.001
  20. Rajâa Boulahjar, Aziz Ouach, Stéphane Bourg, Pascal Bonnet, Olivier Lozach, Laurent Meijer, Christiane Guguen-Guillouzo, Rémy Le Guevel, Saïd Lazar, Mohamed Akssira, Yves Troin, Gérald Guillaumet, Sylvain Routier. Advances in tetrahydropyrido[1,2- a ]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors. European Journal of Medicinal Chemistry 2015;101:274
    https://doi.org/10.1016/j.ejmech.2015.06.046
  21. Lucas M Bronicki, Claire Redin, Severine Drunat, Amélie Piton, Michael Lyons, Sandrine Passemard, Clarisse Baumann, Laurence Faivre, Julien Thevenon, Jean-Baptiste Rivière, Bertrand Isidor, Grace Gan, Christine Francannet, Marjolaine Willems, Murat Gunel, Julie R Jones, Joseph G Gleeson, Jean-Louis Mandel, Roger E Stevenson, Michael J Friez, Arthur S Aylsworth. Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A. Eur J Hum Genet 2015;23:1482
    https://doi.org/10.1038/ejhg.2015.29
  22. Rachel Weitzdoerfer, Nuria Toran, Saraswathi Subramaniyan, Arnold Pollak, Mara Dierssen, Gert Lubec. A cluster of protein kinases and phosphatases modulated in fetal Down syndrome (trisomy 21) brain. Amino Acids 2015;47:1127
    https://doi.org/10.1007/s00726-015-1941-1
  23. Karol Dowjat, Tatyana Adayev, Urszula Wojda, Katarzyna Brzozowska, Anna Barczak, Tomasz Gabryelewicz, Yu-Wen Hwang, Piotr Lewczuk. Abnormalities of DYRK1A-Cytoskeleton Complexes in the Blood Cells as Potential Biomarkers of Alzheimer’s Disease. JAD 2019;72:1059
    https://doi.org/10.3233/JAD-190475
  24. Randall J. Roper, Charles R. Goodlett. Polyphenols: Prevention and Treatment of Human Disease. 2019.
    https://doi.org/10.1016/B978-0-12-813008-7.00035-7
  25. Katharina Rüben, Anne Wurzlbauer, Agnes Walte, Wolfgang Sippl, Franz Bracher, Walter Becker, Yann Herault. Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors. PLoS ONE 2015;10:e0132453
    https://doi.org/10.1371/journal.pone.0132453
  26. B W M van Bon, B P Coe, R Bernier, C Green, J Gerdts, K Witherspoon, T Kleefstra, M H Willemsen, R Kumar, P Bosco, M Fichera, D Li, D Amaral, F Cristofoli, H Peeters, E Haan, C Romano, H C Mefford, I Scheffer, J Gecz, B B A de Vries, E E Eichler. Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID. Mol Psychiatry 2016;21:126
    https://doi.org/10.1038/mp.2015.5
  27. Laura Xicota, Rafael de la Torre. Genetics, Neurology, Behavior, and Diet in Dementia. 2016.
    https://doi.org/10.1016/B978-0-12-815868-5.00050-5