Cited by CrossRef (50)
- Charles R. Goodlett, Megan Stringer, Jonathan LaCombe, Roshni Patel, Joseph M. Wallace, Randall J. Roper. Evaluation of the therapeutic potential of Epigallocatechin-3-gallate (EGCG) via oral gavage in young adult Down syndrome mice. Sci Rep 2020;10
- Esteban J. Rozen, Julia Roewenstrunk, María José Barallobre, Chiara Di Vona, Carole Jung, Ana F. Figueiredo, Jeroni Luna, Cristina Fillat, Maria L. Arbonés, Mariona Graupera, Miguel A. Valverde, Susana de la Luna. DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells. Cell Reports 2018;23:1867
- Laura E. Hawley, Megan Stringer, Abigail J. Deal, Andrew Folz, Charles R. Goodlett, Randall J. Roper. Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model. Neurobiology of Disease 2024;190:106359
- Laura E. Meissner, Ellen F. Macnamara, Precilla D'Souza, John Yang, Gilbert Vezina, Carlos R. Ferreira, Wadih M. Zein, Cynthia J. Tifft, David R. Adams. DYRK1A pathogenic variants in two patients with syndromic intellectual disability and a review of the literature. Molec Gen & Gen Med 2020;8
- Madison S. Strine, Wesley L. Cai, Jin Wei, Mia Madel Alfajaro, Renata B. Filler, Scott B. Biering, Sylvia Sarnik, Ryan D. Chow, Ajinkya Patil, Kasey S. Cervantes, Clayton K. Collings, Peter C. DeWeirdt, Ruth E. Hanna, Kevin Schofield, Christopher Hulme, Silvana Konermann, John G. Doench, Patrick D. Hsu, Cigall Kadoch, Qin Yan, Craig B. Wilen, Frank Kirchhoff. DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner. PLoS Biol 2023;21:e3002097
- Jason K. Russell, Alexander C. Conley, Jo Ellen Wilson, Paul A. Newhouse. . 2023.
- Joshua D. Blazek, Irushi Abeysekera, Jiliang Li, Randall J. Roper. Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomicDyrk1a. Hum. Mol. Genet. 2015;24:5687
- Julie L. Lefebvre. Molecular Mechanisms of Neural Development and Insights into Disease. 2015.
- Farrah Rajabi, Jonathan D. Picker. New Innovations: Therapies for Genetic Conditions. Curr Genet Med Rep 2014;2:113
- Ye Hyung Lee, Eunju Im, Minju Hyun, Joongkyu Park, Kwang Chul Chung. Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation. Journal of Biological Chemistry 2021;296:100245
- Hugo Abarca , Milana Trubnykova , Félix Chavesta , Marco Ordóñez, Evelina Rondón . Importancia de la determinación de variantes en el número de copias en neonatos con aneuploidías autosómicas. biomedica 2021;41:282
- Esti Wahyu Widowati, Sabrina Ernst, Ralf Hausmann, Gerhard Müller-Newen, Walter Becker. Functional characterization of DYRK1A missense variants associated with a syndromic form of intellectual deficiency and autism. 2018;7
- Julie L. Lefebvre, Julie Marocha. Cellular Migration and Formation of Axons and Dendrites. 2018.
- Melissa J. MacPherson, Sarah L. Erickson, Drayden Kopp, Pengqiang Wen, Mohamad-Reza Aghanoori, Shreeya Kedia, Kaylan M.L. Burns, Antonio Vitobello, Frederic Tran Mau-Them, Quentin Thomas, Nina B. Gold, William Brucker, Louise Amlie-Wolf, Karen W. Gripp, Olaf Bodamer, Laurence Faivre, Mikko Muona, Lara Menzies, Julia Baptista, Katie Guegan, Alison Male, Xing-Chang Wei, Guiqiong He, Quan Long, A. Micheil Innes, Guang Yang. Nucleocytoplasmic transport of the RNA-binding protein CELF2 regulates neural stem cell fates. Cell Reports 2021;35:109226
- Masashi Asai, Takashi Kawakubo, Ryotaro Mori, Nobuhisa Iwata. Elucidating Pathogenic Mechanisms of Early-onset Alzheimer's Disease in Down Syndrome Patients. YAKUGAKU ZASSHI 2017;137:801
- Ye Hyung Lee, A-Rum Yoon, Chae-Ok Yun, Kwang Chul Chung. Dual-specificity kinase DYRK3 phosphorylates p62 at the Thr-269 residue and promotes melanoma progression. Journal of Biological Chemistry 2024;300:107206
- Eunju Im, Kwang Chul Chung. Dyrk1A phosphorylates parkin at Ser‐131 and negatively regulates its ubiquitin E3 ligase activity. Journal of Neurochemistry 2015;134:756
- G.F. Sengül, R. Mishra, E. Candiello, P. Schu. Hsc70 phosphorylation patterns and calmodulin regulate AP2 Clathrin-Coated-Vesicle life span for cell adhesion protein transport. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2024;1871:119611
- Xu Zhou, Xiongjin Chen, Tingting Hong, Miaoping Zhang, Yujie Cai, Lili Cui. TTC3-Mediated Protein Quality Control, A Potential Mechanism for Cognitive Impairment. Cell Mol Neurobiol 2022;42:1659
- Sara Anna Bonini, Andrea Mastinu, Giulia Ferrari-Toninelli, Maurizio Memo. Potential Role of Microtubule Stabilizing Agents in Neurodevelopmental Disorders. IJMS 2017;18:1627
- Nianzhuang Qiu, Chenliang Qian, Tingting Guo, Yaling Wang, Hongwei Jin, Mingli Yao, Mei Li, Tianyang Guo, Yuli Lv, Xinxin Si, Song Wu, Hao Wang, Xuehui Zhang, Jie Xia. Discovery of a novel chemotype as DYRK1A inhibitors against Alzheimer's disease: Computational modeling and biological evaluation. International Journal of Biological Macromolecules 2024;269:132024
- Digambar Kumar Waiker, Akash Verma, T.A. Gajendra, Namrata, Anima Roy, Pradeep Kumar, Surendra Kumar Trigun, Saripella Srikrishna, Sairam Krishnamurthy, Vincent Jo Davisson, Sushant Kumar Shrivastava. Design, synthesis, and biological evaluation of some 2-(3-oxo-5,6-diphenyl-1,2,4-triazin-2(3H)-yl)-N-phenylacetamide hybrids as MTDLs for Alzheimer's disease therapy. European Journal of Medicinal Chemistry 2024;271:116409
- Rajâa Boulahjar, Aziz Ouach, Stéphane Bourg, Pascal Bonnet, Olivier Lozach, Laurent Meijer, Christiane Guguen-Guillouzo, Rémy Le Guevel, Saïd Lazar, Mohamed Akssira, Yves Troin, Gérald Guillaumet, Sylvain Routier. Advances in tetrahydropyrido[1,2- a ]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors. European Journal of Medicinal Chemistry 2015;101:274
- Lucas M Bronicki, Claire Redin, Severine Drunat, Amélie Piton, Michael Lyons, Sandrine Passemard, Clarisse Baumann, Laurence Faivre, Julien Thevenon, Jean-Baptiste Rivière, Bertrand Isidor, Grace Gan, Christine Francannet, Marjolaine Willems, Murat Gunel, Julie R Jones, Joseph G Gleeson, Jean-Louis Mandel, Roger E Stevenson, Michael J Friez, Arthur S Aylsworth. Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A. Eur J Hum Genet 2015;23:1482
- Maja Ergović Ravančić, Valentina Obradović. Dietary Supplements - Challenges and Future Research. 2015.
- Wenbin Wan, Lan Cao, Bill Kalionis, Shijin Xia, Xiantao Tai. Applications of Induced Pluripotent Stem Cells in Studying the Neurodegenerative Diseases. Stem Cells International 2015;2015:1
- Laura E. Hawley, Faith Prochaska, Megan Stringer, Charles R. Goodlett, Randall J. Roper. Sexually dimorphic DYRK1A overexpression on postnatal day 15 in the Ts65Dn mouse model of Down syndrome: Effects of pharmacological targeting on behavioral phenotypes. Pharmacology Biochemistry and Behavior 2022;217:173404
- Guillaume Postic, Jean Solarz, Cécile Loubière, Janany Kandiah, Jaysen Sawmynaden, Frederic Adam, Marie Vilaire, Thibaut Léger, Jean‐Michel Camadro, Daniella Balduino Victorino, Marie‐Claude Potier, Eric Bun, Gautier Moroy, Alexandre Kauskot, Olivier Christophe, Nathalie Janel. Over‐expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice. J Cellular Molecular Medi 2023;27:2228
- Cristina Grau, Krisztina Arató, José M. Fernández-Fernández, Aitana Valderrama, Carlos Sindreu, Cristina Fillat, Isidre Ferrer, Susana de la Luna, Xavier Altafaj. DYRK1A-mediated phosphorylation of GluN2A at Ser1048 regulates the surface expression and channel activity of GluN1/GluN2A receptors. Front. Cell. Neurosci. 2014;8
- Mina Yousefelahiyeh, Jingyi Xu, Estibaliz Alvarado, Yang Yu, David Salven, Robert M. Nissen, Arun Rishi. DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B. PLoS ONE 2018;13:e0207779
- Varsha Ananthapadmanabhan, Kathryn H. Shows, Amanda J. Dickinson, Larisa Litovchick. Insights from the protein interaction Universe of the multifunctional “Goldilocks” kinase DYRK1A. Front. Cell Dev. Biol. 2023;11
- Nobuhiro Kurabayashi, Minh Dang Nguyen, Kamon Sanada.
DYRK
1A overexpression enhances
STAT
activity and astrogliogenesis in a Down syndrome mouse model
. EMBO Reports 2015;16:1548
- Arnaud Duchon, Yann Herault. DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome. Front. Behav. Neurosci. 2016;10
- Megan Stringer, Charles R. Goodlett, Randall J. Roper. Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits. Mol Genet Genomic Med 2017;5:451
- Helin Atas-Ozcan, Véronique Brault, Arnaud Duchon, Yann Herault. Dyrk1a from Gene Function in Development and Physiology to Dosage Correction across Life Span in Down Syndrome. Genes 2021;12:1833
- Zinnat Hasina, Nicole Wang, Chi Chiu Wang. Developmental Neuropathology and Neurodegeneration of Down Syndrome: Current Knowledge in Humans. Front. Cell Dev. Biol. 2022;10
- Susana García-Cerro, Noemí Rueda, Verónica Vidal, Sara Lantigua, Carmen Martínez-Cué. Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes. Neurobiology of Disease 2017;106:76
- Qiang Wang, Zhuangzhuang Geng, Yi Gong, Kaitlyn Warren, Haiyan Zheng, Yuka Imamura, Zhonghua Gao. WDR68 is essential for the transcriptional activation of the PRC1-AUTS2 complex and neuronal differentiation of mouse embryonic stem cells. Stem Cell Research 2018;33:206
- Manon Moreau, Maria Carmona-Iragui, Miren Altuna, Lorraine Dalzon, Isabel Barroeta, Marie Vilaire, Sophie Durand, Juan Fortea, Anne-Sophie Rebillat, Nathalie Janel. DYRK1A and Activity-Dependent Neuroprotective Protein Comparative Diagnosis Interest in Cerebrospinal Fluid and Plasma in the Context of Alzheimer-Related Cognitive Impairment in Down Syndrome Patients. Biomedicines 2022;10:1380
- Maria del Mar Muñiz Moreno, Véronique Brault, Marie-Christine Birling, Guillaume Pavlovic, Yann Herault. Preclinical Research in Down Syndrome: Insights for Pathophysiology and Treatments. 2022.
- Ye Hyung Lee, Bo Kyoung Suh, Unghwi Lee, Seung Hyun Ryu, Sung Ryong Shin, Sunghoe Chang, Sang Ki Park, Kwang Chul Chung. DYRK3 phosphorylates SNAPIN to regulate axonal retrograde transport and neurotransmitter release. Cell Death Discov. 2022;8
- Elysabeth D. Otte, Randall J. Roper. Skeletal health in DYRK1A syndrome. Front. Neurosci. 2024;18
- Pinhua Wang, Sunayana Sarkar, Menghuan Zhang, Tingting Xiao, Fenhua Kong, Zhe Zhang, Deepa Balasubramanian, Nandan Jayaram, Sayantan Datta, Ruyu He, Ping Wu, Peng Chao, Ying Zhang, Michael Washburn, Laurence A Florens, Sonal Nagarkar-Jaiswal, Manish Jaiswal, Man Mohan. DYRK1A interacts with the tuberous sclerosis complex and promotes mTORC1 activity. 2024;12
- Rachel Weitzdoerfer, Nuria Toran, Saraswathi Subramaniyan, Arnold Pollak, Mara Dierssen, Gert Lubec. A cluster of protein kinases and phosphatases modulated in fetal Down syndrome (trisomy 21) brain. Amino Acids 2015;47:1127
- Karol Dowjat, Tatyana Adayev, Urszula Wojda, Katarzyna Brzozowska, Anna Barczak, Tomasz Gabryelewicz, Yu-Wen Hwang, Piotr Lewczuk. Abnormalities of DYRK1A-Cytoskeleton Complexes in the Blood Cells as Potential Biomarkers of Alzheimer’s Disease. JAD 2019;72:1059
- Randall J. Roper, Charles R. Goodlett. Polyphenols: Prevention and Treatment of Human Disease. 2019.
- Katharina Rüben, Anne Wurzlbauer, Agnes Walte, Wolfgang Sippl, Franz Bracher, Walter Becker, Yann Herault. Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors. PLoS ONE 2015;10:e0132453
- Barbara Pucelik, Agata Barzowska, Janusz M. Dąbrowski, Anna Czarna. Diabetic Kinome Inhibitors—A New Opportunity for β-Cells Restoration. IJMS 2021;22:9083
- B W M van Bon, B P Coe, R Bernier, C Green, J Gerdts, K Witherspoon, T Kleefstra, M H Willemsen, R Kumar, P Bosco, M Fichera, D Li, D Amaral, F Cristofoli, H Peeters, E Haan, C Romano, H C Mefford, I Scheffer, J Gecz, B B A de Vries, E E Eichler. Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID. Mol Psychiatry 2016;21:126
- Laura Xicota, Rafael de la Torre. Genetics, Neurology, Behavior, and Diet in Dementia. 2016.