Fig. 3. Schematic representation of the domain structure of TDP-43 and FUS. Different protein domains are indicated in different colors. Both proteins contain prion-like and RRM domains. NLS=Nuclear Localization Signal, RRM=RNA Recognition Motif, NES=Nuclear Export signal, Gly-rich=Glycine rich region, SYGQ-rich=Glutamine/Glycine/Serine/Tyrosine rich region, RGG=Arginine/Glycine rich region, ZnF=Zinc finger motif.
© Exp Neurobiol
