Download original image
Fig. 6. Protective effect of LMT497 in vivo ischemic model. All rats were treated MCAO for 90 min and sacrificed 24 hours after occlusion and brain coronal sections were stained with 2% triphenyltetrazolium chloride. (A-H): Intravenous injection of LMT497 (2 mg/kg) twice at 3 h/8 h (A-D) or 10 h/18 h (E-H). (A, E): TTC stained image. (B, F): quantification of infarct volume. (C, G): percentage of edema, (D, H): neurological score. Horizontal bar, median; vertical box, interquartile ranges (Q1 to Q3, minimum/maximum). n=7-10; **p<0.01, ***p<0.001, significantly different from the control group.
Exp Neurobiol 2015;24:31~40
© Exp Neurobiol