Fig. 1. Measurement of edema formation in MCAO mouse brain at reperfusion 24 hr after MCAO injury. (A) At reperfusion 24 hr after MCAO injury, TTC staining showed that white areas were damaged by ischemic injury. White areas reduced in the DHA treatment group compared to experimental control (EC) group. (B) Infarct size (%) was measured at reperfusion 24 hr after MCAO injury. The graph shows the infarct size was significantly attenuated in DHA treatment group. (C) The graph shows that brain edema (%) was significantly reduced in DHA treatment group compared with EC group. Differences were considered significant at *p<0.05. **p<0.0 (t-test via EC group). EC: reperfusion 24 hr after MCAO injury, DHA: DHA treatment and reperfusion 24 hr after MCAO injury.
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