Fig. 2. hCB-EPCs enhance angiogenesis and protect against degeneration in a rat ischemic model. (A, B) Measurement of infarct size of the control, EPC and EPC-C.A1 in the rat model. (A) Densitometric analyses (B), Scale bar, 1000 µm. All values are the means±SEM. ***p<0.001, *p<0.05. (C, D) The behavior test for the control, EPC and EPC-C.A1 in rat model. Limb placement test (C) and Rota-rod test (D). All values are the means±SEM. *p<0.05. (E, F) Confocal images of laminin staining (green) and HuNu staining (red) with the DAPI nuclear marker (blue) in ischemic rats with/without EPC treatment in the absence or presence of co-treatment with COMP-Ang1 (E) and densitometric analyses (F). Scale bar, 50 µm. All values are the means±SEM. ***p<0.001.
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