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Fig. 1. Brain MRI. (A~C) Three weeks after the onset of symptoms, T2-weighted (A), FLAIR (B) and enhanced T1W1 (C) images show a more distinctive lamellate pattern. (D~G) Five months after the initial presentation, T2-weighted (D), FLAIR (E), and enhanced T1W1 (F, G) images show that the size of the lesions is d`iminished and the lamellate pattern has become indistinct. (H, I) Microscopic examination of brain biopsy, showing heavy infiltration of foamy histiocytes with some lymphocytes (H) (Hematoxylin & Eosin staining, ×400). Luxol fast blue staining reveals scattered loss of the myelin sheath (I) (×100). These findings are suggestive of a demyelinating disease.
Exp Neurobiol 2015;24:169~172
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