Fig. 1. NaF decreased peak amplitude and baseline of intrinsic optical signal (IOS) in hippocampal slices. (A) Series of pseudo color images at different time with electrical stimulation was shown for change of light transmittance. (B) Example of light transmittance change of CA1 SR area and measurement of transmittance intensity. (C) Representative example of IOS before and during NaF application. Numbers with red color indicate where IOS recorded. Dotted line indicated that shifting of baseline with application of NaF. (D) Time course of IOS for baseline and amplitude during application of 5 mM NaF. Baseline, peak, and amplitude of IOS are indicated with black circle (●), and gray circle (
) respectively.
