Fig. 3. Effect of PA-5HT on axial, limb, orofacial, and locomotive AIM scores induced by L-DOPA. Axial (A), limb (B), orofacial (C), and locomotive (D) AIMs scores were measured on day 5 and 10 after the L-DOPA treatment (n=8-9). AIMs scored during the 120 min period after L-DOPA treatment in both the groups on day 5. Student's t test,*p<0.05 and **p<0.01, Significant differences between the vehicle- and PA-5HT-treated groups. Data are presented as the mean±SEM. PA-5HT: Palmitoyl serotonin; AIMs: abnormal involuntary movements; L-DOPA: L-3,4-dihydroxyphenylalanine.
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