Fig. 4. Optogenetic rescue of locomotion defects and DA neurodegeneration by EKO. (A) Experimental protocol of optogenetic activation of TH-positive neurons of TH-ChR2-EKO. (B) Locomotion speed of TH-ChR2-EKO Drosophila larvae before and after optogenetic activation. Mean±SEM. ***p<0.001 (one-way ANOVA and Dunnett's multiple comparison test). (C) TH-positive cell number of TH-ChR2-EKO Drosophila larvae before and after optogenetic activation. Mean±SEM. **p<0.01 (one-way ANOVA and Dunnett's multiple comparison test).
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