Fig. 3. (a) Normalized voltage dependence of TFLLR-induced Best1 currents from astrocytes in hippocampal CA1 stratum radiatum region with various anions such as CsCl (n=6), Cs-glutamate (n=8), or gluconate (n=7) in pipette solution. (b) Normalized representative voltage dependence of Best1 current in HEK293T cells recorded with high Ca2+ pipette solution at the indicated intracellular GABA concentrations. In all cases, GABA was substituted for Cl–. (c) Anion permeability of chicken Best1 in liposome recorded by fluorescence-based flux assay.
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