Fig. 1. The change of serum tryptophan metabolites and enzyme activities during aging. Tryptophan metabolites (tryptophan [TRP], kynurenine [KYN], kynurenic acid [KYNA], 3-OH-kynurenine [3-HK]) and their ratios (KYN/TRP ratio, 3-HK/KYN ratio, KYNA/KYN ratio and KYNA/3-HK ratio) in C57BL/6 mice aged 6 weeks, 3 months, 6 months, 8 months (n=6 per timepoint), and 10 months (n=5). Data presented as median and interquartile range. p-values were provided by Kruskal-Wallis test.
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