Fig. 2. The cortex of the (A) right frontal, (B) right parietal, (C) right amygdala, (D) right hippocampus and entorhinal cortex show positive for phosphorylated TAU (pTAU), in the deep edge of the sulci and perivascular area of cortex and amygdala. In the four sectors of the hippocampus, there are flammable shape-neurofibrillary tangles and neuropil threads [A-D: phosphorylated tau (AT8) immunostaining]. (E) Phosphorylated tau (pTAU) positive neurofibrillary tangles and neuropil threads, are most frequent in the perivascular area of the cerebral cortex. (F) In the periaqueductal gray, many neurons contains p-tau positive globose tangles. There is also neuropil thread. (G) The olfactory bulb contains scattered pTAU positive neurons and neuropil threads. (H) 4R-tau is positive for neocortical neurons in the entorhinal cortex [E-G: phosphorylated tau (AT8) immunostaining, H: 4R tau immunostaining].
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