Fig. 4. VPA exposure induced opened chromatin status in Pax6 and Tert genes. (A) The chromatin status markers of Pax6 and Tert genes in VPA-treated NPCs were analyzed through chromatin immunoprecipitation (ChIP). NPCs were cultured with embryos from three different pregnant rats. (B) ChIP was also performed in the VPA-exposed E14 embryonic brains. Results are mean±S.E.M. (n=3). One rat embryo was randomly selected from three different pregnant rats. **p<0.01, ***p<0.001 vs. control.
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