Fig. 2. Immunohistochemistry of macrophages 1 week after spinal cord injury. The representative coronal spinal cord sections 2 mm caudal to epicenter were shown in A. The portion of M2 macrophages (CD206+&ED1+/ED1+) was significantly increased in Agm only 2 mm caudal to epicenter compared to EC (B). Agmatine treatment significantly reduced the number of macrophages (ED1+ cells) 2 mm caudal to epicenter compared to EC (C). Agmatine treatment group (Agm, n=3); Experimental control group (EC, n=3). Scale bar is 200 um. *p<0.05.
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