The percent composition of microbiota at the class, order, and family taxonomic levels in control and ASD subjects
ClassOrderFamily
TaxonMean (%)Fold changep-valueTaxonMean (%)Fold changep-valueTaxonMean (%)Fold changep-value
ControlASDControlASDControlASD
Gammaproteobacteria23.5123.4710.99Oceanospirillales0.212.6212.680.02*Halomonadaceae0.22.61↑ 13.160.02*
Alphaproteobacteria15.294.840.320**Sphingomonadales6.291.980.310**Sphingomonadaceae6.271.98↓ 0.320**
Rhizobiales5.691.050.190**Rhizobiaceae4.580.18↓ 0.040**
Bradyrhizobiaceae0.460.08↓ 0.170.01*
Rickettsiales0.940.10.110.04*mitochondria0.840.1↓ 0.120.02**
Betaproteobacteria10.096.260.620.1Burkholderiales9.55.730.60.11Comamonadaceae2.554.37↑ 1.710.01*
Alcaligenaceae2.530.12↓ 0.050**
Deltaproteobacteria0.20.643.230.01*Desulfovibrionales0.060.539.660**Desulfovibrionaceae0.060.53↑ 9.660**
Bacilli12.8417.551.370.07Lactobacillales7.9211.941.510.07Streptococcaceae1.934.88↑ 2.520.04*
Clostridia11.6315.41.320.18Clostridiales11.5915.381.330.18Unclassified1.061.87↑ 1.750.04*
Clostridiaceae0.441.19↑ 2.700.02*
Eubacteriaceae00.15↑ 146.230.04*
Actinobacteria9.911.091.120.38Actinomycetales7.8410.291.310.09Nocardiaceae0.41.56↑ 3.910.02*
Bifidobacteriales2.060.80.390.03*Bifidobacteriaceae2.060.8↓ 0.390.03*
Bacteroidia5.057.281.440.21Bacteroidales5.057.281.440.21S24-70.842.02↑ 2.400.04*
Flavobacteriia0.561.192.110.03*Flavobacteriales0.561.192.110.03*[Weeksellaceae]0.431.12↑ 2.630.01*
Chloroplast3.811.760.460.03*Streptophyta3.81.680.440.03*Unclassified3.81.68↓ 0.440.03*
Verrucomicrobiae0.522.354.490.02*Verrucomicrobiales0.522.354.490.02*Verrucomicrobiaceae0.522.35↑ 4.490.02*
[Fimbriimonadia]0.38000**[Fimbriimonadales]0.38000**[Fimbriimonadaceae]0.380↓ 0.000**
Deinococci0.070.476.470**Thermales0.030.216.30.02*Thermaceae0.030.21↓ 6.300.02*
TM7-30.050.376.960.05*

Microbiota at the family level whose occupancy was significantly different in ASD subjects are presented with associated higher taxonomy levels. Those occupying 0.1% or higher in either normal healthy or ASD subjects were included. ↑ and ↓ denote an increase and decrease in the percent composition, respectively. Data are the mean percentages. * and ** denote significant differences between the indicated groups at p<0.05 and p<0.01, respectively (Student's t-test).

Exp Neurobiol 2017;26:307~317 https://doi.org/10.5607/en.2017.26.5.307
© Exp Neurobiol