| Strains | Maternal separation paradigm | Behavioral phenotype in MS group in adulthood (compared to controls) | Reference |
|---|---|---|---|
| C57BL/6J | 3 hours MS on P1–P9 | Elevated anxiety-like behavior in EPM and OF. | [14] |
| CD-1 | 3 hours MS on P2–P14 | Decreased anxiety-like behavior in EPM. | [15] |
| CD-1 | 24 hour MS on P12 | No changes in locomotor activity in OF. No change in total time spent immobile in FST. | [16] |
| C57BLl/6NCrlBR | 3 hours MS on P0–P9 | No changes in anxiety-related behavior in DWT. | [17] |
| C57BL/6J | 3 hours MS on P1–P10 | No change in DWT. Decreased anxiety-like behavior in dark phase EZM but increased anxiety in EPM. | [18] |
| 129S1, BALB/cByJ, C57BL/6J, DBA/2J, FVB/NJ | 3 hours MS on P0–13 | No overall changes in anxiety and depressive-related behavior in EPM, LDB, OF and FST. | [10] |
| C57BL/6J | 24 hours MS on P9 | No change in OF activity. Decreased anxiety in EPM. | [19] |
| C57BL/6J | 3 hour MS on P1–14 | Increased anxiety in EPM but no change in anxiety behavior in OF. | [20] |
| C57BL/6J and BALB/c | 3 hours MS on P1–14 | No change in depressive-like behavior in FST. | [21] |
| C57BL/6J and DBA/2J | 24 hour MS on P9 | Lowered anxiety-related behavior in OF. No changes in hole board exploratory activity. No change in depressive-like behavior in FST. | [22] |
| C57BL/6J | 3 hours MS on P2–14 | No change in LDB anxiety-related behavior. NSF behavior not affected. Decreased anxiety-like behavior in OF in last 15 minutes. No change in depressive-like behavior in FST. | [23] |
| CCR7 deficient C57BL/6J | 3 hours MS on P1–14 | No change in anxiety-like behavior in OF and EZM. No change in depressive-like behavior in saccharin preference test. | [24] |
MS, maternal separation; EPM, Elevated Plus Maze; EZM, Elevated Zero Maze; FST, Forced Swim Test; OF, Open field; DWT, Defensive withdrawal test; LDB, Light/dark box; NSF, Novelty suppressed feeding.