Fig. 8. The level of proBDNF is enhanced in EE. (A) Expression of proBDNF in GFAP-positive astrocytes at molecular layer of DG hippocampus (red; proBDNF, green; GFAP). (B) Experimental timeline for histology in enriched environment (EE). (C) Representative confocal images for the immunostained proBDNF (red; proBDNF, blue; DAPI) in DG hippocampus in EE or SC mice. (D) Bar graph showing the comparison of the average intensity of proBDNF immunoreactivity in molecular layer of DG. Unpaired two-tailed-t-test (***p<0.001) (n=16 for SC; n=21 for EE).
© Exp Neurobiol
