Fig. 2. Presynaptic action potential and neurotransmitter release are essential for the generation of activity-dependent IOS and fEPSP. (A, F, K) Schematic diagram for contribution of pre-synaptic action potential and neurotransmitter release. (B, G, L) Representative traces of IOS. Inset: Representative traces of fEPSP. (C, H, M) The percentage of IOS peak. (D, I, N) fEPSP amplitude (mV). (E, J, O) fiber volley of fEPSP (mV). ((C to J) paired t-test (twotailed), (M to O) unpaired t-test (two-tailed), ***p<0.001, ****p<0.0001, NS p>0.05).
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