Fig. 4. The CDK5/p25 signaling pathway in the substantia nigra of MPTP-injected cynomolgus monkeys. (A) The protein levels of CDK5, p35, and p25, and (B) p-ERK in the substantia nigra of saline- and MPTP-injected cynomolgus monkeys were determined using western blotting. ERK was used as the loading control for p-ERK. The data are presented as mean values±SD (n=2). *denotes p<0.05, **denotes p<0.01, and ***denotes p<0.001.
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