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Fig. 2. Chronic immobilization stress (CIS) and glutamine supplementation induced expressional changes of the glutamate-glutamine (Glu-Gln) cycle in the prefrontal cortex. Bars represent the means± SEMs of relative expression levels from immunoblotting. *p<0.05, **p<0.01 (vs. CTL), #p<0.05, ##p<0.01 (vs. STR), one-way ANOVA with Newman-Keuls multiple comparison test as post-hoc analysis. GLT1, glutamate transporter 1; SNATs, sodium-coupled neutral amino acid transporters; GS, glutamate synthetase; GLS2, glutaminase 2; GADs, glutamate decarboxylases; PC, pyruvate carboxylase; GDH, glutamate dehydrogenase. n=7~17. The figure shows a representative group. Molecular weights are marked on the sides of the immunoblots.
Exp Neurobiol 2019;28:270~278
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