Download original image
Fig. 1. Changes in hippocampal matrix metalloproteinase-9 (MMP-9) and angiopoietin-2 (ANG-2) expression over time following bilateral common carotid artery occlusion (BCCAo). (A) Schematic diagram of experimental procedure. (B) Representative western blot for MMP-9 (n=4) and ANG-2 (n=5). (C) Hippocampal MMP-9 levels were significantly increased at 1 week following BCCAo, compared to controls (*). Increased MMP-9 returned to control levels at 4 and 8 weeks (#). (D) Hippocampal ANG-2 also increased at 1 week following BCCAo (*), although its expression levels decreased to control levels at 8 weeks following BCCAo (#, ##).
Exp Neurobiol 2018;27:299~308
© Exp Neurobiol