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Fig. 2. TAP2 suppressed the gene expression of proinflammatory mediators in LPS-stimulated BV2 cells. After pretreatment with TAP2 (10 µM) for 30 minutes, BV2 cells were further incubated with LPS (100 ng/mL) for 3 hours. The mRNA levels of proinflammatory mediators, including TNF-α, IL-1β, IL-6, COX-2, and iNOS, were measured by qPCR. Data are presented as means±SEM (one-way ANOVA with Tukey's post hoc test, ***p<0.001 and **p<0.01 vs. LPS; n=3 per group). LPS, lipopolysaccharide.
Exp Neurobiol 2019;28:352~361
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