Fig. 5. Sociability and social preference determined by time spent in each compartment and approach duration of MK-801-injected mice model in the three-chamber assay and home cage social test. This figure shows the time spent (duration) in each compartment (A) and approach duration (B) of the MK-801-injected mice model compared to controls in the three-chamber social test; the time spent (sniffing duration) by MK-801-injected mice models compared to controls in the home cage social target interaction test (C); home cage two-choice sociability test (D); the social preference test (E~G); the time spent (duration) in each compartment (E) and approach duration (F) of MK-801-injected mice model compared to controls in the three-chamber social test; the time spent (duration) sniffing by MK-801-injected mice models compared to controls in the home cage two-choice social preference test (G). The number of animals per condition was as follows: MK-801 and Veh in the three-chamber assay, n=17; MK-801 and Veh in home cage social target interaction test, n=10, MK-801 and Veh in the home cage two-choice sociability and social preference test, n=13 and n=15, respectively. All data are expressed as the mean±SEM. *p<0.05, **p<0.01, ***p<0.001, Veh, Vehicle group mice; MK-801, MK-801-injected mice.
© Exp Neurobiol
