Fig. 3. Effect of maternal DEHP exposure on PI3K/AKT signaling pathway of pups at PN 14. (A) Western blot bands represent the expression level of proteins in PI3K/AKT/Bcl-2/Bax pathway at PN 14 for males and females. The bar graphs show the results of the semi-quantitative measurement of p-PI3K (B), PI3K (C), p-AKT (D), AKT (E), Bcl-2 (F) and Bax (G). Each bar represents mean±SD. The mean expression in offspring from the 0, 30, 300, and 750 mg/kg/d exposure groups is shown as a fold-change compared to the mean expression in the 0 mg/kg/d group which was ascribed an arbitrary value of 1. With each time point, *p<0.05 vs control, #p<0.05 vs 30 mg/kg/d contamination group (n=6).
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