Fig. 6. MEHP disturbed the PI3K/AKT signaling pathway of CGCs in vitro. (A) Western blot bands represent the expression level of proteins in the PI3K/AKT/Bcl2/Bax pathway in the four MEHP exposure (0, 25, 100 and 250 µM) groups of primary CGCs. The corresponding bar graphs show the results of the semi-quantitative measurement of p-PI3K (B), PI3K (C), p-AKT (D), AKT (E), Bcl-2 (F) and Bax (G). Each bar represents the mean±SD. Mean expression in CGCs from each MEHP exposure group is shown as a fold-change compared to the mean expression in the control group that has been ascribed an arbitrary value of 1. With each time point, *p<0.05 vs control, #p<0.05 vs 250 µM MEHP exposure group, & p<0.05 vs 100 µM MEHP exposure group (n=4).
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