Fig. 11. Di-(2-ethylhexyl) phthalate (DEHP) induce apoptosis of cerebellar granule cells (CGCs). The apoptosis induced by DEHP is associated with inhibition of the PI3K/AKT signaling pathway. Insulin-like growth factor (IGF) 1 may partially protect CGCs from apoptosis and LY294002 aggravated the apoptosis induced by DEHP.

Exp Neurobiol 2018;27:472~488 https://doi.org/10.5607/en.2018.27.6.472

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