Fig. 1. Magnetic resonance imaging (MRI) findings from T2 FLAIR images (A,B) and T2-weighted image (C) obtained in 2005 and T2-weighted images obtained in 2008 (D~F). There is an interval of about 3 years between A~C and D~F. A and D show images from almost the same level, and so are B;C and E;F respectively. (A~C) White matter lesion with T2 hyperintensity is observed. Splenium of corpus callosum (arrow) is also involved (B). Sagittal image shows internal capsule involvement and corpus callosal thining (C). Mild cerebral atrophy and lateral ventricular dilatation is present. (D~F) In 2008, definite disease progression was detected, and the cerebral atrophy and ventricular dilatation worsened. Despite progression of the disease, the subcortical U-fibers are relatively preserved.
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