Fig. 3. Effect of dexmedetomidine on locomotor function. CCI surgery and intrathecal dexmedetomidine administration at the dosage used in the present study did not affect locomotor function. Naïve, normal rats; Sham, surgery without CCI; CCI, chronic constriction injury; CCI+NS, intrathecally administered 20 µl normal saline following CCI; CCI+DEX, intrathecally administered 2.5 µg/20 µl dexmedetomidine following CCI (Mean±SEM, n=6, five trials).
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