Fig. 2. CAP improves functional recovery without neurorestoration. (A) Experimental diagram of CNTF receptor alpha neutralizing antibody (CNTFRαNAb) and MPP+ injection, capsaicin single injection and amphetamine-induced behavioral test (B) Cumulative amphetamine-induced ipsilateral rotations. *p<0.05, significantly different from 9 weeks. (C) Photomicrographs of TH+ cells in the SN and TH+ fibers in the striatum (STR). Scale bars: 400 µm (SN), 2 mm (STR). Magnification: 4× (SN), 1.25× (STR). (D) Number of TH+ or Nissl+ cells in the SN pars compacta (SNpc). (E) Optical density of TH+ fibers in the STR. D and E, *p<0.05, significantly different from control. Mean±s.e.m.; B, Student t-Test and D and E, One way ANOVA with Newman-Keuls analysis.
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