Fig. 2. Time course of the effects of HAL (A) and CLZ (C) treatment on DA release in the rat striatum (n=5 per drug and dose condition). Time-averaged (from the time of drug treatment to the end of the study) percentage changes from baseline for each dose of HAL (B) and CLZ (D). HAL and CLZ represent the haloperidol- and clozapine-treated groups. The low and high doses of HAL and CLZ were 1 and 7 mg/kg body weight and 10 and 54 mg/kg body weight, respectively. The value is designated as 0% at time 0, and drugs were treated at time=0 min. Values are the mean±SEM.
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