List of previously reported studies associated with diffusion MR imaging
| Authors | Secies | Year | Scanner | Data/ Analysis program | Finding |
|---|---|---|---|---|---|
| Calabrese et al. [10] | 2-Wild type (C57BL/6) Mice | 2015 | 9.4 T | Diffusion MR image |
Ipsilateral connectivity was higher than contralateral connectivity. Significant correlation was detected between ABA neuronal tracer data and diffusion tractography data. |
| Cong et al. [11] | 6 MitoPark Mice (Parkinson disease)/ 9 wildtype (C57BL/6) Mice | 2016 | 7T | Diffusion MR image/ T2* map/ Cerebral blood flow MR images |
T2* of the MitoPark group showed significant reductions in the striatum and substantia nigra compared with control groups. ADC values of the MitoPark group showed significant reductions in the SN compared with the control group. |
| Hübner et al. [12] | Cuprizone treated (CUPR) C57BL/6N mice | 2017 | 7T | rsfMRI data/ T2-weighted image/ Diffusion MR images | CUPR induced pathology decreases average functional connectivity strength within the whole functional connectivity matrix. |
| Perlbarg et al. [13] | 15 Sprague Dawley rats (10 rats: 6-OHDA injection. 5 rats: physiological solution injection) | 2018 | 11.7 T | T2-weighted image/Multi-slice echo-planar image/ Diffusion MR image |
There was increased FA value in the ipsilateral and contralateral striatum. |
| Lenglet et al. [14] | 4 healthy humans | 2012 | 7T | T1-weighted images/T2-weighted images/Susceptibilityweighted images/Diffusion MR image |
Connections of STN to GP were higher for GPi than for GPe. STN-striatum connections were weak. |
| Milardi et al. [15] | 15 human subjects | 2016 | 3T | 3DT1-weighted image/3DT2-weighted image/Diffusion MR image |
This study found the presence of direct connections between SN and Dentate nucleus. Dentate was widely projected to the GP.. |
| Plantinga et al. [16] | A formalin fixed human brain specimen | 2016 | 7T | Diffusion MR image |
Direct connections within the basal ganglia (STN, STN-GP, STN-SN, SNr-SNc etc.) were shown in this study. STN-GPi connections were fewer than the STNSNr connections, that reflect a relatively important role for the STN-SNr connection in human. |
| Pujol et al. [8] | 5 healthy subjects | 2017 | 3T | T1-weighted image/T2-weighted image/ Diffusion MR image |
This study investigated the white matter connectivity between the STN and GP. A number of fibers interconnecting GPi arose from the ventral-medial STN. |