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Fig. 5. Deficiency of GMF reduces NF-kB activation and neuroinflammatory proteins expression in SN of midbrain from mice subjected toTBI. Weight drop TBI in the cortical region significantly increases the activation of NF-kB, neuroinflammatory proteins such as iNOS and COX2 expression in SN region of the midbrain of WT and GMF-KO mice as determined by western blot (A and C). Bar graph shows the quantitation of blot intensity (B, D and E) expression as compared to the controls. Values are presented as meanĀ±SEM (n=6). *p<0.05 control vs TBI subjected mice; #p<0.05 GMF-KO TBI subjected mice vs WT TBI subjected mice.
Exp Neurobiol 2020;29:230~248
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