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Fig. 6. Absence of GMF improves TBI induced neurotrophic factors expression in SN of the midbrain. Induction of TBI by weight drop method in the cortical region causes significant reduction in neurotrophic factors such as BDNF and GDNF expressions in the SN region of the midbrain of WT and GMF-KO mice as determined by western blot (A). Bar graphs show the quantitation of the western blot intensity with BDNF (B) and GDNF (C) as compared to the controls. Values are presented as meanĀ±SEM (n=6). *p<0.05 control vs. TBI subjected mice; #p<0.05 GMF-KO TBI subjected mice vs WT TBI subjected mice.
Exp Neurobiol 2020;29:230~248
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