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Fig. 8. GMF is involved in TBI induced axonal injury in dopaminergic neurons of the midbrain. TBI-induced cortical brain tissue damage causes significant axonal injury of the TH-positive dopaminergic neurons in the SN region of the midbrain of WT and GMF-KO mice as determined by immunofluorescence (A; Insets B). Bar graph shows the measured axonal length of TH-positive dopaminergic neurons in the field (C), as compared to the controls. Values are presented as meanĀ±SEM (n=6). *p<0.05 control vs TBI subjected mice; #p<0.05 GMF-KO TBI subjected mice vs WT TBI subjected mice.
Exp Neurobiol 2020;29:230~248
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