Fig. 9. GMF influences the TBI induced UCHL1 and TH positive dopaminergic neurons expressions in the median eminence. Induction of TBI in the cortical region enhances UCHL-1 protein expression and reduces TH-positive tanycytes expression in the median eminence as determined by immunofluorescence. Representative images show a qualitative enhancement of UCHL-1 expression and reduced TH-positive tanycytes in the median eminence after weight drop induced TBI in mice brain at 72 h time point (A). Bar graphs show the number of TH-Positive tanycytes in the median eminence after TBI of WT and GMF-KO mice (B). Scale bar 50 µm. *p<0.05 control vs TBI subjected mice; #p<0.05 GMF-KO TBI subjected mice vs WT TBI subjected mice.
© Exp Neurobiol
