Quantitative expression of molecules of cell survival- and growth-related pathways in the rat retina
| Molecules | Sham | Injury | AAV2-GFP | AAV2-Pim-1 |
|---|---|---|---|---|
| Stat3 | 1.00 | 5.14±1.33 | 4.54±3.06 | 12.11±2.38 |
| p-Stat3 | 1.00 | 4.10±1.72 | 7.21±1.44 | 12.58±1.62 |
| Akt1 | 1.00 | 1.12±0.13 | 0.29±0.16 | 0.88±0.06 |
| p-Akt1 | 1.00 | 0.59±0.32 | 0.72±0.17 | 1.70±0.35 |
| Akt2 | 1.00 | 0.47±0.06 | 0.33±0.16 | 1.74±0.65 |
| p-Akt2 | 1.00 | 0.23±0.09 | 0.43±0.12 | 1.37±0.12 |
| Erk1/2 | 1.00 | 1.06±0.10 | 1.27±0.32 | 1.19±0.21 |
| p-Erk1/2 | 1.00 | 1.40±0.09 | 1.36±0.67 | 1.22±0.41 |
| SOCS1 | 1.00 | 1.87±0.24 | 3.09±1.28 | 0.85±0.43 |
| SOCS3 | 1.00 | 1.84±0.34 | 4.26±0.96 | 2.55±0.80 |
Compared with AAV2-GFP group, *p<0.05, **p<0.01, ***p<0.001, #p>0.05.