Fig. 1. Schematic presentation of the experimental design and magnetic resonance-based assessment for assessing the post stroke outcome. (A) The in vivo experimental study followed this scheme. (B) Magnetic resonance (MR) angiography of non-human primate models of focal cerebral ischemia. The occlusion and reperfusion of the middle cerebral artery (MCA) were confirmed using MR angiography. Left: the yellow rectangle indicates the circle of Willis located at the base of the brain. Right: MCA blood flow can be observed during reperfusion. (C) Representative 3D maximum intensity projection views of fluid-attenuated inversion recovery (FLAIR) images of the ischemic lesion 24 h after reperfusion. BA, basilar artery; ICA, internal carotid artery; MCA, middle cerebral artery; L, left; R, right; P, posterior; A, anterior; S, superior; I, inferior.
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