Fig. 5. Antidepressant-like effect of MCH is mediated by MCHR1. The FST was examined during the last 4 min of the test period and (A) immobility, (B) climbing, and (C) swimming behaviors were recorded in stressed mice. In the TST, (D) immobility behavior in mice were observed during the 6 min test period. n=5/group. Data represent the meansĀ±SEM. ***p<0.001, *p<0.01 vs. Nor group, ###p<0.001, #p<0.05 vs. STR group, $$$p<0.001, $p<0.05 vs. MCH group. Nor, normal; STR, stress; MCH, melanin-concentrating hormone.
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