Electrophysiological properties of pyramidal and interneurons in single-, pair-exposed rats and naïve rats in mPFC

Pyramidal Interneuron
Single Pair Naïve Single Pair Naïve
Cm (pA) 58.92±4.17 (n=21) 67.78±4.73 (n=18) 56.42±3.73 (n=36) 24.83±1.74 (n=19) 27.02±0.9 (n=17) 30.07±3.49 (n=18)
Rm (MΩ) 94.23±8.99** (n=21) 103.25±16.9* (n=18) 209.29±24.78 (n=36) 273.5±56.75 (n=19) 284.28±35.37 (n=17) 282.04±41.32 (n=18)
IR (MΩ) 140±10 (n=25) 120±6* (n=20) 180±8 (n=38) 190±10* (n=17) 260±30## (n=18) 250±10 (n=19)
RMP (mV) -74.79±2.7 (n=23) -70.58±1.54 (n=17) -73±3.01 (n=7) -65.63±2.82 (n=12) -64.12±2.28 (n=17) -66.43±3.24 (n=7)

mPFC, medial prefrontal cortex; IR, input resistance; Cm, membrane capacitance; Rm, membrane resistance; RMP, resting membrane potential. Two-way ANOVA, Bonferroni post-hoc test: *p<0.05, **p<0.01, compared with Naïve; ## p<0.01, compared with Single.
Exp Neurobiol 2021;30:48~58 https://doi.org/10.5607/en20038
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